Phylogenetic analysis of Newcastle disease viruses isolated from commercial poultry in Mozambique (2011–2016)

• Published in: Virus genes Vol. 52; no. 5; pp. 748 - 753
• Main Authors: Mapaco, Lourenço P., Monjane, Iolanda V. A., Nhamusso, Antonieta E., Viljoen, Gerrit J., Dundon, William G., Achá, Sara J.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.10.2016; Springer Nature B.V
• Subjects: Animals; Biomedical and Life Sciences; Biomedicine; China; Genotype; Medical Microbiology; Mozambique; Newcastle Disease - virology; Newcastle disease virus - genetics; Newcastle disease virus - isolation & purification; Phylogeny; Plant Sciences; Poultry - virology; Poultry Diseases - virology; RNA, Viral - genetics; Sequence Analysis, DNA - methods; South Africa; Virology; Phylogenetic analysis; Genotype VIIh; Newcastle disease; Mozambique; Poultry
• ISSN: 0920-8569; 1572-994X
• DOI: 10.1007/s11262-016-1362-6

The complete sequence of the fusion (F) protein gene from 11 Newcastle disease viruses (NDVs) isolated from commercial poultry in Mozambique between 2011 and 2016 has been generated. The F gene cleavage site motif for all 11 isolates was 112 RRRKRF 117 indicating that the viruses are virulent. A phylogenetic analysis using the full F gene sequence revealed that the viruses clustered within genotype VIIh and showed a higher similarity to NDVs from South Africa, China and Southeast Asia than to viruses previously described in Mozambique in 1994, 1995 and 2005. The identification of these new NDVs has important implications for Newcastle disease management and control in Mozambique.