Cardiovascular Disease Risk in Survivors of Breast Cancer

• Published in: Current treatment options in cardiovascular medicine Vol. 21; no. 12; p. 79
• Main Authors: Sharma, Avinash V., Reddin, Gemma, Forrestal, Brian, Barac, Ana
• Format: Journal Article
• Language: English
• Published: New York Springer US 09.12.2019; Springer Nature B.V
• Subjects: Body mass index; Breast cancer; Cardiology; Cardiovascular disease; Exercise; Hormone replacement therapy; Medicine; Medicine & Public Health; Mortality; Obesity; Section Editor; Topical Collection on Women’s Health; Women’s Health (M Wood; Chemotherapy cardiotoxicity; Cardio-oncology; Breast cancer survivors
• ISSN: 1092-8464; 1534-3189
• DOI: 10.1007/s11936-019-0788-2

Purpose of review Early detection and improved treatment in breast cancer have resulted in an increased number of survivors. Cardiovascular disease now remains an important cause for morbidity and mortality in this population. There is a growing gap in the knowledge about the optimal long-term cardiovascular management of this population. Findings Breast cancer and cardiovascular disease share a number of common risk factors. Different breast cancer treatment modalities, including anthracyclines, radiation, and hormonal therapy, can act in synergy with preexisting and/or new cardiovascular risk factors to result in significant cardiovascular disease. Summary We summarize the recent evidence about cardiovascular effects of breast cancer therapy and recommendations for their diagnosis and management during the cancer treatment continuum into survivorship. We also present current research initiatives and how they inform clinical care.