Antioxidant, Antimicrobial and Physicochemical Properties of Turmeric Extract-Loaded Nanostructured Lipid Carrier (NLC)

The objective of this research was to encapsulate turmeric extract as a water-insoluble bioactive material by nanostructured lipid carrier (NLC). Turmeric extract loaded NLC (T-NLC) was produced by high shear homogenization method. The average size of T-NLC was 112.4nm and it showed good physical st...

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Bibliographic Details
Published inColloid and interface science communications Vol. 22; pp. 18 - 24
Main Authors Karimi, Nayyer, Ghanbarzadeh, Babak, Hamishehkar, Hamed, Mehramuz, Bahareh, Kafil, Hossein Samadi
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.01.2018
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Summary:The objective of this research was to encapsulate turmeric extract as a water-insoluble bioactive material by nanostructured lipid carrier (NLC). Turmeric extract loaded NLC (T-NLC) was produced by high shear homogenization method. The average size of T-NLC was 112.4nm and it showed good physical stability, and a sustained release pattern. Higuchi model fit in vitro release of turmeric extract from NLC the best. The antioxidant activity of T-NLC was significantly higher than free turmeric extract. The results of microbiological tests by agar-dilution method showed that NLC had higher antimicrobial activity than free turmeric extract against all examined gram negative bacilli microorganisms. The results indicate that T-NLC can be used in food products with high functional effects. [Display omitted] •Tumeric extract-NLC had high Antioxidant activity.•Tumeric extract-NLC had high antibacterial activity against Escherichia coli.•Tumeric extract-NLC showed character of a perfect functional food.
ISSN:2215-0382
2215-0382
DOI:10.1016/j.colcom.2017.11.006