Self-controlled super-selective arterial spin labelling

• Published in: European radiology Vol. 28; no. 3; pp. 1227 - 1233
• Main Authors: Lindner, Thomas, Austein, Friederike, Jansen, Olav, Helle, Michael
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2018; Springer Nature B.V
• Subjects: Adult; Arteries; Cerebral Arteries - diagnostic imaging; Cerebral Arteries - physiology; Cerebrovascular Circulation - physiology; Colonies & territories; Control methods; Diagnostic Radiology; Electron Spin Resonance Spectroscopy - methods; Female; Flow mapping; Healthy Volunteers; Humans; Image acquisition; Imaging; Internal Medicine; Interventional Radiology; Labeling; Magnetic Resonance Angiography - methods; Male; Mapping; Medicine; Medicine & Public Health; Neuro; Neuroradiology; Perfusion; Radiology; Spin labeling; Spin Labels; Territory; Ultrasound; Veins & arteries; Young Adult; Super-selective; Flow territory mapping; Self-control; Arterial spin labelling; Perfusion
• ISSN: 0938-7994; 1432-1084; 1432-1084
• DOI: 10.1007/s00330-017-5066-7

Objectives Arterial spin labelling (ASL) is a method of non-contrast-enhanced perfusion imaging that is generally based on the acquisition of two images which must be subtracted in order to obtain perfusion-weighted images. This is also the case for some flow territory mapping approaches that require the acquisition of two images for each artery of interest, thereby prolonging scan time and yielding largely redundant information. The aim of this study is to accelerate flow territory mapping using ASL by eliminating the acquisition of a control condition. Methods Using super-selective ASL, only one artery of interest is tagged, while the contralateral arteries are in a state similar to the control condition. By using an arithmetic combination of the label images of all territories, selective images of flow territories can be obtained without the need to acquire an additional control condition. This approach for obtaining artery-selective perfusion-weighted images without acquiring a control condition is presented in this study and is referred to as "self-controlled super-selective ASL". Results Quantitative perfusion measurements were similar to conventional super-selective and non-selective perfusion imaging across all subjects. Conclusion Super-selective arterial spin labelling can be performed without acquiring a control image. Key Points • An accelerated method of flow territory mapping is presented. • Super-selective arterial spin labelling is performed without a control condition. • A new approach for calculating individual flow territories is presented. • The presented technique is compared to established approaches. • The outcome is similar to that using conventional techniques.