Prebiotic Chemistry: The Role of Trimetaphosphate in Prebiotic Chemical Evolution

Life’s origins have always been a scientific puzzle. Understanding the production of biomolecules is crucial for understanding the evolution of life on Earth. Numerous studies on trimetaphosphate have been conducted in the field of prebiotic chemistry. However, its role in prebiotic chemistry has be...

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Published inFrontiers in chemistry Vol. 10; p. 941228
Main Authors Gan, Dingwei, Ying, Jianxi, Zhao, Yufen
Format Journal Article
LanguageEnglish
Published Frontiers Media S.A 13.07.2022
Subjects
Chemistry
nucleotide
origin of life
peptide
prebiotic chemistry
trimetaphosphate
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Summary:Life’s origins have always been a scientific puzzle. Understanding the production of biomolecules is crucial for understanding the evolution of life on Earth. Numerous studies on trimetaphosphate have been conducted in the field of prebiotic chemistry. However, its role in prebiotic chemistry has been documented infrequently in the review literature. The goal of this thesis is to review the role of trimetaphosphate in the early Earth’s biomolecule synthesis and phosphorylation. Additionally, various trimetaphosphate-mediated reaction pathways are discussed, as well as the role of trimetaphosphate in prebiotic chemistry. Finally, in our opinion, interactions between biomolecules should be considered in prebiotic synthesis scenarios since this may result in some advances in subsequent research on this subject. The research establishes an essential and opportune foundation for an in-depth examination of the “mystery of life".
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Matthew A. Pasek, University of South Florida, United States
Edited by: Qinheng Zheng, University of California, San Francisco, United States
This article was submitted to Chemical Biology, a section of the journal Frontiers in Chemistry
Reviewed by: Brian Cafferty, Beam Therapeutics, United States
ISSN:2296-2646
2296-2646
DOI:10.3389/fchem.2022.941228