Weight and body mass index in Parkinson's disease patients after deep brain stimulation surgery

• Published in: Parkinsonism & related disorders Vol. 11; no. 4; pp. 247 - 252
• Main Authors: Tuite, Paul J., Maxwell, Robert E., Ikramuddin, Sayeed, Kotzd, Catherine M., Billingtond, Charles J., Laseski, Maggie A., Thielen, Scott D.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2005
• Subjects: Body Mass Index; Deep Brain Stimulation; Energy Metabolism; Female; Humans; Male; Middle Aged; Obesity; Obesity - etiology; Parkinson Disease - metabolism; Parkinson Disease - therapy; Parkinson's disease; Retrospective Studies; Weight; Weight Gain; Obesity; Parkinson's disease; Deep brain stimulation; Weight
• ISSN: 1353-8020; 1873-5126
• DOI: 10.1016/j.parkreldis.2005.01.006

A retrospective chart review characterizing changes in 17 male and 10 female Parkinson's disease (PD) patients undergoing deep brain stimulation (DBS) surgery indicated that 6 mo before surgery, patients lost a mean of 5.1 lbs, whereas in the 6 mo after surgery, subjects gained a mean of 10.1 lbs; 22% gained more than 14 lbs. In 10 patients followed an additional 6 mo, weight gain continued. This weight gain may be associated with decreased energy expenditure due to subsidence of chronic tremor. The magnitude of gain underscores the need for proactive management of body weight in PD patients undergoing DBS.