Diagnosis of Recurrent Fracture in a Pediatric Cohort
Significant fracture history in children is defined as having at least one vertebral fracture, at least 2 fractures by age 10, or at least 3 fractures by age 19. Between September 2011 and December 2014, clinical data were collected on children with a significant fracture history that attended a maj...
Saved in:
Published in | Calcified tissue international Vol. 103; no. 5; pp. 529 - 539 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
New York
Springer US
01.11.2018
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Significant fracture history in children is defined as having at least one vertebral fracture, at least 2 fractures by age 10, or at least 3 fractures by age 19. Between September 2011 and December 2014, clinical data were collected on children with a significant fracture history that attended a major Australian children’s hospital. Fifty-six patients were identified as having 305 fractures in total, including 44 vertebral fractures. 18% of patients (10/56) were diagnosed with osteogenesis imperfecta (OI) by a bone health expert, molecular testing or both, and they sustained 23% of all fractures (71/305). Analysis of serum bone biochemistry showed all median values to be within a normal range and no clinically significant differences between patients with and without OI. The DXA and pQCT derived bone mineral density (BMD) and bone mineral content (BMC)
Z
scores were reduced overall. DXA derived total body and lumbar spine areal BMD-for-age and BMC-for-age
Z
scores were significantly lower in children who had vertebral fractures or who were later diagnosed with OI. Similarly, pQCT performed on radii and tibiae showed
Z
scores significantly less than zero. pQCT-derived limb muscle cross sectional area
Z
scores were significantly lower in the OI subgroup. In conclusion, this study describes the bone phenotype of children referred to a tertiary hospital clinic for recurrent fractures and highlights a subset of children with previously undiagnosed OI, but a larger cohort without classic OI. Thus it can be clinically challenging to differentiate between children with OI type 1 (mild phenotype) and non-OI children without bone densitometry and genetic testing. We conclude that recurrent fractures in children should prompt a comprehensive bone and systemic health assessment to eliminate an underlying pathology. |
---|---|
AbstractList | Significant fracture history in children is defined as having at least one vertebral fracture, at least 2 fractures by age 10, or at least 3 fractures by age 19. Between September 2011 and December 2014, clinical data were collected on children with a significant fracture history that attended a major Australian children’s hospital. Fifty-six patients were identified as having 305 fractures in total, including 44 vertebral fractures. 18% of patients (10/56) were diagnosed with osteogenesis imperfecta (OI) by a bone health expert, molecular testing or both, and they sustained 23% of all fractures (71/305). Analysis of serum bone biochemistry showed all median values to be within a normal range and no clinically significant differences between patients with and without OI. The DXA and pQCT derived bone mineral density (BMD) and bone mineral content (BMC)
Z
scores were reduced overall. DXA derived total body and lumbar spine areal BMD-for-age and BMC-for-age
Z
scores were significantly lower in children who had vertebral fractures or who were later diagnosed with OI. Similarly, pQCT performed on radii and tibiae showed
Z
scores significantly less than zero. pQCT-derived limb muscle cross sectional area
Z
scores were significantly lower in the OI subgroup. In conclusion, this study describes the bone phenotype of children referred to a tertiary hospital clinic for recurrent fractures and highlights a subset of children with previously undiagnosed OI, but a larger cohort without classic OI. Thus it can be clinically challenging to differentiate between children with OI type 1 (mild phenotype) and non-OI children without bone densitometry and genetic testing. We conclude that recurrent fractures in children should prompt a comprehensive bone and systemic health assessment to eliminate an underlying pathology. Significant fracture history in children is defined as having at least one vertebral fracture, at least 2 fractures by age 10, or at least 3 fractures by age 19. Between September 2011 and December 2014, clinical data were collected on children with a significant fracture history that attended a major Australian children's hospital. Fifty-six patients were identified as having 305 fractures in total, including 44 vertebral fractures. 18% of patients (10/56) were diagnosed with osteogenesis imperfecta (OI) by a bone health expert, molecular testing or both, and they sustained 23% of all fractures (71/305). Analysis of serum bone biochemistry showed all median values to be within a normal range and no clinically significant differences between patients with and without OI. The DXA and pQCT derived bone mineral density (BMD) and bone mineral content (BMC) Z scores were reduced overall. DXA derived total body and lumbar spine areal BMD-for-age and BMC-for-age Z scores were significantly lower in children who had vertebral fractures or who were later diagnosed with OI. Similarly, pQCT performed on radii and tibiae showed Z scores significantly less than zero. pQCT-derived limb muscle cross sectional area Z scores were significantly lower in the OI subgroup. In conclusion, this study describes the bone phenotype of children referred to a tertiary hospital clinic for recurrent fractures and highlights a subset of children with previously undiagnosed OI, but a larger cohort without classic OI. Thus it can be clinically challenging to differentiate between children with OI type 1 (mild phenotype) and non-OI children without bone densitometry and genetic testing. We conclude that recurrent fractures in children should prompt a comprehensive bone and systemic health assessment to eliminate an underlying pathology. |
Author | Little, D. G. Biggin, A. Briody, J. Munns, C. F. Fiscaletti, M. Coorey, C. P. Schindeler, A. |
Author_xml | – sequence: 1 givenname: M. orcidid: 0000-0003-2092-0691 surname: Fiscaletti fullname: Fiscaletti, M. email: melissa.fiscaletti@umontreal.ca organization: Institute of Endocrinology and Diabetes, The Children’s Hospital at Westmead, Department of Endocrinology & Diabetes, The Children’s Hospital at Westmead – sequence: 2 givenname: C. P. surname: Coorey fullname: Coorey, C. P. organization: Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney – sequence: 3 givenname: A. surname: Biggin fullname: Biggin, A. organization: Institute of Endocrinology and Diabetes, The Children’s Hospital at Westmead, Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney – sequence: 4 givenname: J. surname: Briody fullname: Briody, J. organization: Department of Nuclear Medicine, The Children’s Hospital at Westmead – sequence: 5 givenname: D. G. surname: Little fullname: Little, D. G. organization: Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Department of Orthopaedics, The Children’s Hospital at Westmead, Orthopaedic Research & Biotechnology Unit, The Children’s Hospital at Westmead – sequence: 6 givenname: A. surname: Schindeler fullname: Schindeler, A. organization: Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Orthopaedic Research & Biotechnology Unit, The Children’s Hospital at Westmead – sequence: 7 givenname: C. F. surname: Munns fullname: Munns, C. F. organization: Institute of Endocrinology and Diabetes, The Children’s Hospital at Westmead, Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29943187$$D View this record in MEDLINE/PubMed |
BookMark | eNp1kE1LxDAQhoOsuB_6A7xIwYuX6CRNk-Yoq6vCgiIK3kKaJmuX3WZN2oP_3pauCoK5zCHPvDPzTNGo9rVF6JTAJQEQVxGA0hQDyTEwJjE_QBPCUoohp2KEJkAEwZKLtzGaxrgGIIxzfoTGVEqWklxMUHZT6VXtYxUT75Jna9oQbN0ki6BN0wabVHWikydbVroJlUnm_t2H5hgdOr2J9mRfZ-h1cfsyv8fLx7uH-fUSm1TQBhPumHFFSUhWgDaUOBCusNIUtuSGZWleSt6tIsoMcm5kQQVQqx0wlzFKZTpDF0PuLviP1sZGbato7Gaja-vbqChkMsto2r0ZOv-Drn0b6m67nspz1h_cUWSgTPAxBuvULlRbHT4VAdU7VYNT1TlVvVPFu56zfXJbbG350_EtsQPoAMTuq17Z8Dv6_9QvxmeBHw |
CitedBy_id | crossref_primary_10_1002_jbm4_10174 crossref_primary_10_1007_s12020_018_1822_y crossref_primary_10_3389_fendo_2023_1266986 crossref_primary_10_1007_s40272_021_00487_7 crossref_primary_10_3389_fendo_2020_00576 crossref_primary_10_1210_clinem_dgz294 crossref_primary_10_1007_s11914_021_00667_x crossref_primary_10_1002_jbm4_10782 |
Cites_doi | 10.1210/jc.2015-2175 10.1016/j.jocd.2014.01.005 10.1002/jbmr.5650090918 10.1136/adc.82.6.452 10.1359/jbmr.051215 10.1007/s11914-017-0388-6 10.1002/jbmr.5650110716 10.1002/jbmr.414 10.1007/s00198-017-4031-2 10.1002/jbmr.1579 10.1542/peds.2007-2079 10.1007/s00223-016-0233-4 10.1016/B978-0-12-382040-2.10019-X 10.1016/j.jpeds.2016.08.075 10.1038/sj.ijo.0801207 10.1016/S0140-6736(78)90763-8 10.1016/j.jpeds.2015.10.058 10.1016/j.bone.2005.06.007 10.1359/JBMR.050820 10.1359/jbmr.060601 10.1007/s11914-014-0227-y 10.1093/aje/kwh052 10.1002/jbmr.155 10.1016/j.jocd.2007.11.002 10.1097/MPG.0000000000001216 10.1016/j.jocd.2014.01.003 10.1016/j.bone.2009.05.016 10.1007/s002239900387 10.1359/jbmr.2001.16.7.1337 10.1159/000381047 10.1016/S0140-6736(04)16051-0 10.1136/ip.7.1.77 10.1016/j.injury.2007.01.036 10.1097/01241398-200309000-00010 10.1002/jbmr.218 10.1359/jbmr.040902 10.3109/17453671003628780 10.1210/jc.2013-1272 10.1007/s00198-010-1333-z 10.1016/j.jocd.2014.01.004 10.1016/S0022-3476(03)00187-2 10.1016/S0065-3101(24)00183-X |
ContentType | Journal Article |
Copyright | Springer Science+Business Media, LLC, part of Springer Nature 2018 Calcified Tissue International is a copyright of Springer, (2018). All Rights Reserved. |
Copyright_xml | – notice: Springer Science+Business Media, LLC, part of Springer Nature 2018 – notice: Calcified Tissue International is a copyright of Springer, (2018). All Rights Reserved. |
DBID | NPM AAYXX CITATION 3V. 7QP 7RV 7X7 7XB 88E 8AO 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. KB0 LK8 M0S M1P M7P NAPCQ PQEST PQQKQ PQUKI PRINS 7X8 |
DOI | 10.1007/s00223-018-0449-6 |
DatabaseName | PubMed CrossRef ProQuest Central (Corporate) Calcium & Calcified Tissue Abstracts ProQuest Nursing & Allied Health Database Health Medical collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central ProQuest Central Essentials Biological Science Collection ProQuest Central ProQuest Natural Science Collection ProQuest One Community College ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection (Proquest) (PQ_SDU_P3) ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) Biological Sciences Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) Biological Science Database Nursing & Allied Health Premium ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic |
DatabaseTitle | PubMed CrossRef ProQuest Central Student ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central China ProQuest Central Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Biological Science Collection ProQuest Medical Library (Alumni) ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest Nursing & Allied Health Source (Alumni) ProQuest One Academic Calcium & Calcified Tissue Abstracts ProQuest Central (Alumni) MEDLINE - Academic |
DatabaseTitleList | PubMed MEDLINE - Academic ProQuest Central Student |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Anatomy & Physiology |
EISSN | 1432-0827 |
EndPage | 539 |
ExternalDocumentID | 10_1007_s00223_018_0449_6 29943187 |
Genre | Research Support, Non-U.S. Gov't Journal Article |
GrantInformation_xml | – fundername: Osteoporosis Australia/ANZBMS |
GroupedDBID | --- -4W -56 -5G -BR -EM -Y2 -~C .55 .86 .VR 06C 06D 0R~ 0VY 199 1N0 2.D 203 23N 28- 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2VQ 2~H 30V 36B 3O- 3V. 4.4 406 408 409 40D 40E 53G 5GY 5QI 5RE 5VS 67Z 6NX 78A 7RV 7X7 88E 8AO 8FE 8FH 8FI 8FJ 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AABYN AAFGU AAHNG AAIAL AAJKR AANXM AANZL AAPBV AARHV AARTL AATNV AATVU AAUYE AAWCG AAWTL AAYFA AAYIU AAYQN AAYTO ABBBX ABBXA ABDZT ABECU ABELW ABFGW ABFTV ABHLI ABHQN ABIPD ABJNI ABJOX ABKAS ABKCH ABKTR ABMNI ABMQK ABNWP ABPLI ABPTK ABQBU ABSXP ABTEG ABTHY ABTKH ABTMW ABULA ABUWG ABWNU ABXPI ACBMV ACBRV ACBXY ACBYP ACGFS ACHSB ACHXU ACIGE ACIPQ ACKNC ACMDZ ACMLO ACOKC ACOMO ACPRK ACTTH ACVWB ACWMK ADBBV ADHIR ADIMF ADINQ ADJJI ADKNI ADKPE ADMDM ADOAH ADOXG ADRFC ADTPH ADURQ ADYFF ADYPR ADZKW AEBTG AEEQQ AEFIE AEFTE AEGAL AEGNC AEJHL AEJRE AEKMD AENEX AEOHA AEPYU AEQTP AESKC AESTI AETLH AEVLU AEVTX AEXYK AFEXP AFFNX AFKRA AFLOW AFNRJ AFQWF AFWTZ AFZKB AGAYW AGDGC AGGBP AGGDS AGJBK AGMZJ AGQMX AGWIL AGWZB AGYKE AHAVH AHBYD AHIZS AHMBA AHSBF AHYZX AIAKS AIIXL AILAN AIMYW AITGF AJBLW AJDOV AJRNO AJZVZ AKMHD AKQUC ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AOCGG AOSHJ ARMRJ ASPBG AVWKF AXYYD AZFZN B-. BA0 BBNVY BBWZM BDATZ BENPR BGNMA BHPHI BKEYQ BPHCQ BVXVI CAG CCPQU COF CS3 CSCUP DDRTE DL5 DNIVK DPUIP EBD EBLON EBS EIOEI EJD EMB EMOBN EN4 ESBYG EX3 F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ6 GQ7 GQ8 GXS HCIFZ HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ I09 IHE IJ- IKXTQ IMOTQ ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KDC KOV KOW KPH L7B LAS LK8 LLZTM M1P M4Y M7P MA- N2Q NAPCQ NB0 NDZJH NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OAM P19 P2P P9S PF0 PQQKQ PROAC PSQYO PT4 PT5 Q2X QOK QOR QOS R89 R9I RHV RIG RNI RNS ROL RPX RRX RSV RZK S16 S1Z S26 S27 S28 S37 S3B SAP SBL SBY SCLPG SDH SDM SHX SISQX SJYHP SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZN T13 T16 TSG TSK TSV TT1 TUC U2A U9L UG4 UKHRP UNUBA UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WJK WK8 WOW X7M YLTOR Z45 Z7U Z7V Z7W Z7X Z82 Z87 Z8O Z8P Z8Q Z8V Z91 ZGI ZMTXR ZOVNA ~02 ~EX AACDK AAEOY AAJBT AAQLM AASML ABAKF ACAOD ACDTI ACZOJ AEFQL AEMSY AFBBN AGQEE AGRTI AIGIU ALIPV H13 NPM AAYXX CITATION 7QP 7XB 8FK AZQEC DWQXO GNUQQ K9. PQEST PQUKI PRINS 7X8 |
ID | FETCH-LOGICAL-c372t-16f4cfbd115b0ac21f07fbe9cbed6c4538d969947d5086c9b2702eaf04f542293 |
IEDL.DBID | 7X7 |
ISSN | 0171-967X |
IngestDate | Sat Aug 17 03:06:50 EDT 2024 Fri Sep 13 01:53:27 EDT 2024 Thu Sep 12 21:02:43 EDT 2024 Sat Sep 28 08:37:48 EDT 2024 Sat Dec 16 12:22:59 EST 2023 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 5 |
Keywords | Peripheral quantitative computed tomography Recurrent fracture pQCT Osteogenesis imperfecta Dual-energy X-ray absorptiometry Fracture Bone density Bone mineral density Bone DXA |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c372t-16f4cfbd115b0ac21f07fbe9cbed6c4538d969947d5086c9b2702eaf04f542293 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0003-2092-0691 |
PMID | 29943187 |
PQID | 2058844318 |
PQPubID | 48445 |
PageCount | 11 |
ParticipantIDs | proquest_miscellaneous_2059552333 proquest_journals_2058844318 crossref_primary_10_1007_s00223_018_0449_6 pubmed_primary_29943187 springer_journals_10_1007_s00223_018_0449_6 |
PublicationCentury | 2000 |
PublicationDate | 2018-11-01 |
PublicationDateYYYYMMDD | 2018-11-01 |
PublicationDate_xml | – month: 11 year: 2018 text: 2018-11-01 day: 01 |
PublicationDecade | 2010 |
PublicationPlace | New York |
PublicationPlace_xml | – name: New York – name: United States |
PublicationSubtitle | and Musculoskeletal Research |
PublicationTitle | Calcified tissue international |
PublicationTitleAbbrev | Calcif Tissue Int |
PublicationTitleAlternate | Calcif Tissue Int |
PublicationYear | 2018 |
Publisher | Springer US Springer Nature B.V |
Publisher_xml | – name: Springer US – name: Springer Nature B.V |
References | Hill, Fasano, Guandalini, Hoffenberg, Levy, Reilly (CR20) 2016; 63 Deere, Sayers, Viljakainen, Lawlor, Sattar, Kemp (CR26) 2013; 98 Clark, Ness, Bishop, Tobias (CR34) 2006; 21 Palomo, Glorieux, Schoenau, Rauch (CR44) 2016; 169 Rauch, Glorieux (CR9) 2004; 363 Rauch, Schoenau (CR18) 2008; 8 Moustaki, Lariou, Petridou (CR3) 2001; 7 Reinus, McAlister, Schranck, Chines, Whyte (CR42) 1998; 62 Makitie, Kampe, Taylan, Makitie (CR10) 2017; 15 Lu, Briody, Ogle, Morley, Humphries, Allen (CR14) 1994; 9 Rauch, Land, Cornibert, Schoenau, Glorieux (CR43) 2005; 37 Korula, Titmuss, Biggin, Munns (CR4) 2015; 28 Skaggs, Loro, Pitukcheewanont, Tolo, Gilsanz (CR39) 2001; 16 Jones, Williams, Goulding (CR22) 2004; 159 Farr, Funk, Chen, Lisse, Blew, Lee (CR25) 2011; 26 CR11 Cooper, Dennison, Leufkens, Bishop, van Staa (CR29) 2004; 19 Cheng, Xu, Nicholson, Tylavsky, Lyytikainen, Wang (CR37) 2009; 45 Bardai, Ward, Trejo, Moffatt, Glorieux, Rauch (CR41) 2017; 28 Marini (CR40) 1988; 35 Farr, Tomas, Chen, Lisse, Lohman, Going (CR36) 2011; 26 Mayranpaa, Makitie, Kallio (CR47) 2010; 25 Sillence, Rimoin (CR8) 1978; 311 Munns, Shaw, Kiely, Specker, Thacher, Ozono (CR19) 2016; 101 Glorieux, Rowe, Glorieux, Pettifor, Juppner (CR7) 2012 Genant, Jergas, Palermo, Nevitt, Valentin, Black (CR13) 1996; 11 Olney, Mazur, Pike, Froyen, Ramirez-Garnica, Loveless (CR45) 2008; 121 Moyer-Mileur, Quick, Murray (CR16) 2008; 11 Kalkwarf, Laor, Bean (CR38) 2011; 22 Hogler, Briody, Woodhead, Chan, Cowell (CR15) 2003; 143 (CR12) 2013 Ferrari, Chevalley, Bonjour, Rizzoli (CR35) 2006; 21 Rauch, Schoenau (CR17) 2005; 5 Landin (CR1) 1983; 202 CR21 Crabtree, Arabi, Bachrach, Fewtrell, El-Hajj Fuleihan, Kecskemethy (CR33) 2014; 17 Brudvik, Hove (CR46) 2003; 23 Bishop, Arundel, Clark, Dimitri, Farr, Jones (CR5) 2014; 17 Bianchi, Leonard, Bechtold, Hogler, Mughal, Schonau (CR6) 2014; 17 Clark (CR2) 2014; 12 Hedstrom, Svensson, Bergstrom, Michno (CR28) 2010; 81 Mayranpaa, Viljakainen, Toiviainen-Salo, Kallio, Makitie (CR32) 2012; 27 Kyriakou, Shepherd, Mason, Ahmed (CR48) 2016; 179 Goulding, Taylor, Jones, McAuley, Manning, Williams (CR24) 2000; 24 Kelley, Crabtree, Zemel (CR27) 2017; 100 Goulding, Grant, Williams (CR23) 2005; 20 Lyons, Sellstrom, Delahunty, Loeb, Varilo (CR31) 2000; 82 Rennie, Court-Brown, Mok, Beattie (CR30) 2007; 38 DL Skaggs (449_CR39) 2001; 16 ML Bianchi (449_CR6) 2014; 17 RA Lyons (449_CR31) 2000; 82 N Bishop (449_CR5) 2014; 17 W Hogler (449_CR15) 2003; 143 HJ Kalkwarf (449_CR38) 2011; 22 449_CR11 F Rauch (449_CR43) 2005; 37 SL Ferrari (449_CR35) 2006; 21 MK Mayranpaa (449_CR47) 2010; 25 RC Olney (449_CR45) 2008; 121 G Bardai (449_CR41) 2017; 28 JN Farr (449_CR25) 2011; 26 EM Clark (449_CR2) 2014; 12 A Kyriakou (449_CR48) 2016; 179 EM Hedstrom (449_CR28) 2010; 81 FH Glorieux (449_CR7) 2012 PW Lu (449_CR14) 1994; 9 DO Sillence (449_CR8) 1978; 311 L Rennie (449_CR30) 2007; 38 EM Clark (449_CR34) 2006; 21 F Rauch (449_CR17) 2005; 5 A Goulding (449_CR23) 2005; 20 LJ Moyer-Mileur (449_CR16) 2008; 11 RE Makitie (449_CR10) 2017; 15 MK Mayranpaa (449_CR32) 2012; 27 S Korula (449_CR4) 2015; 28 S Cheng (449_CR37) 2009; 45 C Cooper (449_CR29) 2004; 19 JC Kelley (449_CR27) 2017; 100 JN Farr (449_CR36) 2011; 26 National Health and Medical Research Council (449_CR12) 2013 F Rauch (449_CR18) 2008; 8 449_CR21 T Palomo (449_CR44) 2016; 169 IE Jones (449_CR22) 2004; 159 CF Munns (449_CR19) 2016; 101 JC Marini (449_CR40) 1988; 35 WR Reinus (449_CR42) 1998; 62 M Moustaki (449_CR3) 2001; 7 HK Genant (449_CR13) 1996; 11 C Brudvik (449_CR46) 2003; 23 K Deere (449_CR26) 2013; 98 NJ Crabtree (449_CR33) 2014; 17 F Rauch (449_CR9) 2004; 363 ID Hill (449_CR20) 2016; 63 A Goulding (449_CR24) 2000; 24 LA Landin (449_CR1) 1983; 202 |
References_xml | – volume: 101 start-page: 394 issue: 2 year: 2016 end-page: 415 ident: CR19 article-title: Global consensus recommendations on prevention and management of nutritional rickets publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2015-2175 contributor: fullname: Ozono – volume: 17 start-page: 281 issue: 2 year: 2014 end-page: 294 ident: CR6 article-title: Bone health in children and adolescents with chronic diseases that may affect the skeleton: the 2013 ISCD pediatric official positions publication-title: J Clin Densitom doi: 10.1016/j.jocd.2014.01.005 contributor: fullname: Schonau – volume: 9 start-page: 1451 issue: 9 year: 1994 end-page: 1458 ident: CR14 article-title: Bone mineral density of total body, spine, and femoral neck in children and young adults: a cross-sectional and longitudinal study publication-title: J Bone Miner Res doi: 10.1002/jbmr.5650090918 contributor: fullname: Allen – volume: 82 start-page: 452 issue: 6 year: 2000 end-page: 455 ident: CR31 article-title: Incidence and cause of fractures in European districts publication-title: Arch Dis Child doi: 10.1136/adc.82.6.452 contributor: fullname: Varilo – volume: 21 start-page: 501 issue: 4 year: 2006 end-page: 507 ident: CR35 article-title: Childhood fractures are associated with decreased bone mass gain during puberty: an early marker of persistent bone fragility? publication-title: J Bone Miner Res doi: 10.1359/jbmr.051215 contributor: fullname: Rizzoli – volume: 15 start-page: 303 issue: 4 year: 2017 end-page: 310 ident: CR10 article-title: Recent discoveries in monogenic disorders of childhood bone fragility publication-title: Curr Osteoporos Rep doi: 10.1007/s11914-017-0388-6 contributor: fullname: Makitie – volume: 11 start-page: 984 issue: 7 year: 1996 end-page: 996 ident: CR13 article-title: Comparison of semiquantitative visual and quantitative morphometric assessment of prevalent and incident vertebral fractures in osteoporosis The Study of Osteoporotic Fractures Research Group publication-title: J Bone Miner Res doi: 10.1002/jbmr.5650110716 contributor: fullname: Black – volume: 26 start-page: 2217 issue: 9 year: 2011 end-page: 2225 ident: CR25 article-title: Skeletal muscle fat content is inversely associated with bone strength in young girls publication-title: J Bone Miner Res doi: 10.1002/jbmr.414 contributor: fullname: Lee – volume: 28 start-page: 2095 issue: 7 year: 2017 end-page: 2101 ident: CR41 article-title: Molecular diagnosis in children with fractures but no extraskeletal signs of osteogenesis imperfecta publication-title: Osteoporos Int doi: 10.1007/s00198-017-4031-2 contributor: fullname: Rauch – volume: 27 start-page: 1413 issue: 6 year: 2012 end-page: 1424 ident: CR32 article-title: Impaired bone health and asymptomatic vertebral compressions in fracture-prone children: a case-control study publication-title: J Bone Miner Res doi: 10.1002/jbmr.1579 contributor: fullname: Makitie – volume: 121 start-page: 890 issue: 5 year: 2008 end-page: 897 ident: CR45 article-title: Healthy children with frequent fractures: how much evaluation is needed? publication-title: Pediatrics doi: 10.1542/peds.2007-2079 contributor: fullname: Loveless – volume: 202 start-page: 1 year: 1983 end-page: 109 ident: CR1 article-title: Fracture patterns in children. Analysis of 8,682 fractures with special reference to incidence, etiology and secular changes in a Swedish urban population 1950–1979 publication-title: Acta Orthop Scand Suppl contributor: fullname: Landin – volume: 100 start-page: 514 issue: 5 year: 2017 end-page: 527 ident: CR27 article-title: Bone density in the obese child: clinical considerations and diagnostic challenges publication-title: Calcif Tissue Int doi: 10.1007/s00223-016-0233-4 contributor: fullname: Zemel – start-page: 511 year: 2012 end-page: 539 ident: CR7 article-title: Osteogenesis Imperfecta publication-title: Pediatric bone: biology and diseases doi: 10.1016/B978-0-12-382040-2.10019-X contributor: fullname: Juppner – volume: 179 start-page: 219 year: 2016 end-page: 225 ident: CR48 article-title: Prevalence of vertebral fractures in children with suspected osteoporosis publication-title: J Pediatr doi: 10.1016/j.jpeds.2016.08.075 contributor: fullname: Ahmed – volume: 24 start-page: 627 issue: 5 year: 2000 end-page: 632 ident: CR24 article-title: Overweight and obese children have low bone mass and area for their weight publication-title: Int J Obes Relat Metab Disord doi: 10.1038/sj.ijo.0801207 contributor: fullname: Williams – volume: 311 start-page: 1041 issue: 8072 year: 1978 end-page: 1042 ident: CR8 article-title: Classification of osteogenesis imperfect publication-title: Lancet doi: 10.1016/S0140-6736(78)90763-8 contributor: fullname: Rimoin – volume: 169 start-page: 232 year: 2016 end-page: 237 ident: CR44 article-title: Body composition in children and adolescents with osteogenesis imperfecta publication-title: J Pediatr doi: 10.1016/j.jpeds.2015.10.058 contributor: fullname: Rauch – volume: 37 start-page: 634 issue: 5 year: 2005 end-page: 641 ident: CR43 article-title: High and low density in the same bone: a study on children and adolescents with mild osteogenesis imperfecta publication-title: Bone doi: 10.1016/j.bone.2005.06.007 contributor: fullname: Glorieux – volume: 8 start-page: 217 issue: 3 year: 2008 end-page: 226 ident: CR18 article-title: Peripheral quantitative computed tomography of the proximal radius in young subjects—new reference data and interpretation of results publication-title: J Musculoskelet Neuronal Interact contributor: fullname: Schoenau – ident: CR21 – volume: 20 start-page: 2090 issue: 12 year: 2005 end-page: 2096 ident: CR23 article-title: Bone and body composition of children and adolescents with repeated forearm fractures publication-title: J Bone Miner Res doi: 10.1359/JBMR.050820 contributor: fullname: Williams – volume: 21 start-page: 1489 issue: 9 year: 2006 end-page: 1495 ident: CR34 article-title: Association between bone mass and fractures in children: a prospective cohort study publication-title: J Bone Miner Res doi: 10.1359/jbmr.060601 contributor: fullname: Tobias – volume: 12 start-page: 272 issue: 3 year: 2014 end-page: 278 ident: CR2 article-title: The epidemiology of fractures in otherwise healthy children publication-title: Curr Osteoporos Rep doi: 10.1007/s11914-014-0227-y contributor: fullname: Clark – year: 2013 ident: CR12 publication-title: Summary guide for the management of overweight and obesity in primary care – volume: 159 start-page: 343 issue: 4 year: 2004 end-page: 350 ident: CR22 article-title: Associations of birth weight and length, childhood size, and smoking with bone fractures during growth: evidence from a birth cohort study publication-title: Am J Epidemiol doi: 10.1093/aje/kwh052 contributor: fullname: Goulding – volume: 25 start-page: 2752 issue: 12 year: 2010 end-page: 2759 ident: CR47 article-title: Decreasing incidence and changing pattern of childhood fractures: a population-based study publication-title: J Bone Miner Res doi: 10.1002/jbmr.155 contributor: fullname: Kallio – volume: 11 start-page: 283 issue: 2 year: 2008 end-page: 294 ident: CR16 article-title: Peripheral quantitative computed tomography of the tibia: pediatric reference values publication-title: J Clin Densitom doi: 10.1016/j.jocd.2007.11.002 contributor: fullname: Murray – volume: 63 start-page: 156 issue: 1 year: 2016 end-page: 165 ident: CR20 article-title: NASPGHAN clinical report on the diagnosis and treatment of gluten-related disorders publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/MPG.0000000000001216 contributor: fullname: Reilly – volume: 17 start-page: 225 issue: 2 year: 2014 end-page: 242 ident: CR33 article-title: Dual-energy X-ray absorptiometry interpretation and reporting in children and adolescents: the revised 2013 ISCD pediatric official positions publication-title: J Clin Densitom doi: 10.1016/j.jocd.2014.01.003 contributor: fullname: Kecskemethy – volume: 45 start-page: 480 issue: 3 year: 2009 end-page: 486 ident: CR37 article-title: Low volumetric BMD is linked to upper-limb fracture in pubertal girls and persists into adulthood: a seven-year cohort study publication-title: Bone doi: 10.1016/j.bone.2009.05.016 contributor: fullname: Wang – volume: 62 start-page: 17 issue: 1 year: 1998 end-page: 20 ident: CR42 article-title: Differing lumbar vertebral mineralization rates in ambulatory pediatric patients with osteogenesis imperfecta publication-title: Calcif Tissue Int doi: 10.1007/s002239900387 contributor: fullname: Whyte – volume: 16 start-page: 1337 issue: 7 year: 2001 end-page: 1342 ident: CR39 article-title: Increased body weight and decreased radial cross-sectional dimensions in girls with forearm fractures publication-title: J Bone Miner Res doi: 10.1359/jbmr.2001.16.7.1337 contributor: fullname: Gilsanz – volume: 28 start-page: 210 year: 2015 end-page: 225 ident: CR4 article-title: A practical approach to children with recurrent fractures publication-title: Endocr Dev doi: 10.1159/000381047 contributor: fullname: Munns – volume: 363 start-page: 1377 issue: 9418 year: 2004 end-page: 1385 ident: CR9 article-title: Osteogenesis imperfecta publication-title: Lancet doi: 10.1016/S0140-6736(04)16051-0 contributor: fullname: Glorieux – ident: CR11 – volume: 35 start-page: 391 year: 1988 end-page: 426 ident: CR40 article-title: Osteogenesis imperfecta: comprehensive management publication-title: Adv Pediatr contributor: fullname: Marini – volume: 7 start-page: 77 issue: 1 year: 2001 ident: CR3 article-title: Cross country variation of fractures in the childhood population. Is the origin biological or “accidental”? publication-title: Injury Prev doi: 10.1136/ip.7.1.77 contributor: fullname: Petridou – volume: 38 start-page: 913 issue: 8 year: 2007 end-page: 922 ident: CR30 article-title: The epidemiology of fractures in children publication-title: Injury doi: 10.1016/j.injury.2007.01.036 contributor: fullname: Beattie – volume: 23 start-page: 629 issue: 5 year: 2003 end-page: 634 ident: CR46 article-title: Childhood fractures in Bergen, Norway: identifying high-risk groups and activities publication-title: J Pediatr Orthop doi: 10.1097/01241398-200309000-00010 contributor: fullname: Hove – volume: 26 start-page: 380 issue: 2 year: 2011 end-page: 387 ident: CR36 article-title: Lower trabecular volumetric BMD at metaphyseal regions of weight-bearing bones is associated with prior fracture in young girls publication-title: J Bone Miner Res doi: 10.1002/jbmr.218 contributor: fullname: Going – volume: 5 start-page: 119 issue: 2 year: 2005 end-page: 126 ident: CR17 article-title: Peripheral quantitative computed tomography of the distal radius in young subjects—new reference data and interpretation of results publication-title: J Musculoskelet Neuronal Interact contributor: fullname: Schoenau – volume: 19 start-page: 1976 issue: 12 year: 2004 end-page: 1981 ident: CR29 article-title: Epidemiology of childhood fractures in Britain: a study using the general practice research database publication-title: J Bone Miner Res doi: 10.1359/jbmr.040902 contributor: fullname: van Staa – volume: 81 start-page: 148 issue: 1 year: 2010 end-page: 153 ident: CR28 article-title: Epidemiology of fractures in children and adolescents publication-title: Acta Orthop doi: 10.3109/17453671003628780 contributor: fullname: Michno – volume: 98 start-page: E1041 issue: 6 year: 2013 end-page: E1049 ident: CR26 article-title: Distinct relationships of intramuscular and subcutaneous fat with cortical bone: findings from a cross-sectional study of young adult males and females publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2013-1272 contributor: fullname: Kemp – volume: 22 start-page: 607 issue: 2 year: 2011 end-page: 616 ident: CR38 article-title: Fracture risk in children with a forearm injury is associated with volumetric bone density and cortical area (by peripheral QCT) and areal bone density (by DXA) publication-title: Osteoporos Int doi: 10.1007/s00198-010-1333-z contributor: fullname: Bean – volume: 17 start-page: 275 issue: 2 year: 2014 end-page: 280 ident: CR5 article-title: Fracture prediction and the definition of osteoporosis in children and adolescents: the ISCD 2013 pediatric official positions publication-title: J Clin Densitom doi: 10.1016/j.jocd.2014.01.004 contributor: fullname: Jones – volume: 143 start-page: 81 issue: 1 year: 2003 end-page: 88 ident: CR15 article-title: Importance of lean mass in the interpretation of total body densitometry in children and adolescents publication-title: J Pediatr doi: 10.1016/S0022-3476(03)00187-2 contributor: fullname: Cowell – volume: 169 start-page: 232 year: 2016 ident: 449_CR44 publication-title: J Pediatr doi: 10.1016/j.jpeds.2015.10.058 contributor: fullname: T Palomo – volume: 202 start-page: 1 year: 1983 ident: 449_CR1 publication-title: Acta Orthop Scand Suppl contributor: fullname: LA Landin – volume: 63 start-page: 156 issue: 1 year: 2016 ident: 449_CR20 publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/MPG.0000000000001216 contributor: fullname: ID Hill – volume: 100 start-page: 514 issue: 5 year: 2017 ident: 449_CR27 publication-title: Calcif Tissue Int doi: 10.1007/s00223-016-0233-4 contributor: fullname: JC Kelley – ident: 449_CR21 – volume: 98 start-page: E1041 issue: 6 year: 2013 ident: 449_CR26 publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2013-1272 contributor: fullname: K Deere – volume: 25 start-page: 2752 issue: 12 year: 2010 ident: 449_CR47 publication-title: J Bone Miner Res doi: 10.1002/jbmr.155 contributor: fullname: MK Mayranpaa – volume: 21 start-page: 1489 issue: 9 year: 2006 ident: 449_CR34 publication-title: J Bone Miner Res doi: 10.1359/jbmr.060601 contributor: fullname: EM Clark – volume: 159 start-page: 343 issue: 4 year: 2004 ident: 449_CR22 publication-title: Am J Epidemiol doi: 10.1093/aje/kwh052 contributor: fullname: IE Jones – volume: 62 start-page: 17 issue: 1 year: 1998 ident: 449_CR42 publication-title: Calcif Tissue Int doi: 10.1007/s002239900387 contributor: fullname: WR Reinus – volume: 143 start-page: 81 issue: 1 year: 2003 ident: 449_CR15 publication-title: J Pediatr doi: 10.1016/S0022-3476(03)00187-2 contributor: fullname: W Hogler – volume: 363 start-page: 1377 issue: 9418 year: 2004 ident: 449_CR9 publication-title: Lancet doi: 10.1016/S0140-6736(04)16051-0 contributor: fullname: F Rauch – volume: 45 start-page: 480 issue: 3 year: 2009 ident: 449_CR37 publication-title: Bone doi: 10.1016/j.bone.2009.05.016 contributor: fullname: S Cheng – volume: 20 start-page: 2090 issue: 12 year: 2005 ident: 449_CR23 publication-title: J Bone Miner Res doi: 10.1359/JBMR.050820 contributor: fullname: A Goulding – volume: 101 start-page: 394 issue: 2 year: 2016 ident: 449_CR19 publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2015-2175 contributor: fullname: CF Munns – volume: 17 start-page: 225 issue: 2 year: 2014 ident: 449_CR33 publication-title: J Clin Densitom doi: 10.1016/j.jocd.2014.01.003 contributor: fullname: NJ Crabtree – volume: 26 start-page: 2217 issue: 9 year: 2011 ident: 449_CR25 publication-title: J Bone Miner Res doi: 10.1002/jbmr.414 contributor: fullname: JN Farr – volume: 121 start-page: 890 issue: 5 year: 2008 ident: 449_CR45 publication-title: Pediatrics doi: 10.1542/peds.2007-2079 contributor: fullname: RC Olney – ident: 449_CR11 – volume: 82 start-page: 452 issue: 6 year: 2000 ident: 449_CR31 publication-title: Arch Dis Child doi: 10.1136/adc.82.6.452 contributor: fullname: RA Lyons – volume: 35 start-page: 391 year: 1988 ident: 449_CR40 publication-title: Adv Pediatr doi: 10.1016/S0065-3101(24)00183-X contributor: fullname: JC Marini – volume: 38 start-page: 913 issue: 8 year: 2007 ident: 449_CR30 publication-title: Injury doi: 10.1016/j.injury.2007.01.036 contributor: fullname: L Rennie – volume: 8 start-page: 217 issue: 3 year: 2008 ident: 449_CR18 publication-title: J Musculoskelet Neuronal Interact contributor: fullname: F Rauch – volume: 17 start-page: 281 issue: 2 year: 2014 ident: 449_CR6 publication-title: J Clin Densitom doi: 10.1016/j.jocd.2014.01.005 contributor: fullname: ML Bianchi – volume: 11 start-page: 283 issue: 2 year: 2008 ident: 449_CR16 publication-title: J Clin Densitom doi: 10.1016/j.jocd.2007.11.002 contributor: fullname: LJ Moyer-Mileur – volume: 12 start-page: 272 issue: 3 year: 2014 ident: 449_CR2 publication-title: Curr Osteoporos Rep doi: 10.1007/s11914-014-0227-y contributor: fullname: EM Clark – volume: 27 start-page: 1413 issue: 6 year: 2012 ident: 449_CR32 publication-title: J Bone Miner Res doi: 10.1002/jbmr.1579 contributor: fullname: MK Mayranpaa – volume: 19 start-page: 1976 issue: 12 year: 2004 ident: 449_CR29 publication-title: J Bone Miner Res doi: 10.1359/jbmr.040902 contributor: fullname: C Cooper – volume: 28 start-page: 2095 issue: 7 year: 2017 ident: 449_CR41 publication-title: Osteoporos Int doi: 10.1007/s00198-017-4031-2 contributor: fullname: G Bardai – volume: 179 start-page: 219 year: 2016 ident: 449_CR48 publication-title: J Pediatr doi: 10.1016/j.jpeds.2016.08.075 contributor: fullname: A Kyriakou – volume: 16 start-page: 1337 issue: 7 year: 2001 ident: 449_CR39 publication-title: J Bone Miner Res doi: 10.1359/jbmr.2001.16.7.1337 contributor: fullname: DL Skaggs – volume: 22 start-page: 607 issue: 2 year: 2011 ident: 449_CR38 publication-title: Osteoporos Int doi: 10.1007/s00198-010-1333-z contributor: fullname: HJ Kalkwarf – volume: 28 start-page: 210 year: 2015 ident: 449_CR4 publication-title: Endocr Dev doi: 10.1159/000381047 contributor: fullname: S Korula – volume: 81 start-page: 148 issue: 1 year: 2010 ident: 449_CR28 publication-title: Acta Orthop doi: 10.3109/17453671003628780 contributor: fullname: EM Hedstrom – volume: 23 start-page: 629 issue: 5 year: 2003 ident: 449_CR46 publication-title: J Pediatr Orthop doi: 10.1097/01241398-200309000-00010 contributor: fullname: C Brudvik – volume: 7 start-page: 77 issue: 1 year: 2001 ident: 449_CR3 publication-title: Injury Prev doi: 10.1136/ip.7.1.77 contributor: fullname: M Moustaki – volume: 11 start-page: 984 issue: 7 year: 1996 ident: 449_CR13 publication-title: J Bone Miner Res doi: 10.1002/jbmr.5650110716 contributor: fullname: HK Genant – volume: 9 start-page: 1451 issue: 9 year: 1994 ident: 449_CR14 publication-title: J Bone Miner Res doi: 10.1002/jbmr.5650090918 contributor: fullname: PW Lu – volume: 24 start-page: 627 issue: 5 year: 2000 ident: 449_CR24 publication-title: Int J Obes Relat Metab Disord doi: 10.1038/sj.ijo.0801207 contributor: fullname: A Goulding – volume-title: Summary guide for the management of overweight and obesity in primary care year: 2013 ident: 449_CR12 contributor: fullname: National Health and Medical Research Council – volume: 17 start-page: 275 issue: 2 year: 2014 ident: 449_CR5 publication-title: J Clin Densitom doi: 10.1016/j.jocd.2014.01.004 contributor: fullname: N Bishop – volume: 21 start-page: 501 issue: 4 year: 2006 ident: 449_CR35 publication-title: J Bone Miner Res doi: 10.1359/jbmr.051215 contributor: fullname: SL Ferrari – volume: 37 start-page: 634 issue: 5 year: 2005 ident: 449_CR43 publication-title: Bone doi: 10.1016/j.bone.2005.06.007 contributor: fullname: F Rauch – volume: 26 start-page: 380 issue: 2 year: 2011 ident: 449_CR36 publication-title: J Bone Miner Res doi: 10.1002/jbmr.218 contributor: fullname: JN Farr – volume: 5 start-page: 119 issue: 2 year: 2005 ident: 449_CR17 publication-title: J Musculoskelet Neuronal Interact contributor: fullname: F Rauch – start-page: 511 volume-title: Pediatric bone: biology and diseases year: 2012 ident: 449_CR7 doi: 10.1016/B978-0-12-382040-2.10019-X contributor: fullname: FH Glorieux – volume: 311 start-page: 1041 issue: 8072 year: 1978 ident: 449_CR8 publication-title: Lancet doi: 10.1016/S0140-6736(78)90763-8 contributor: fullname: DO Sillence – volume: 15 start-page: 303 issue: 4 year: 2017 ident: 449_CR10 publication-title: Curr Osteoporos Rep doi: 10.1007/s11914-017-0388-6 contributor: fullname: RE Makitie |
SSID | ssj0014666 |
Score | 2.3365686 |
Snippet | Significant fracture history in children is defined as having at least one vertebral fracture, at least 2 fractures by age 10, or at least 3 fractures by age... |
SourceID | proquest crossref pubmed springer |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 529 |
SubjectTerms | Age Biochemistry Biomedical and Life Sciences Bone mineral content Bone mineral density Cell Biology Children Computed tomography Densitometry Dual energy X-ray absorptiometry Endocrinology Fractures Genetic screening Life Sciences Medical diagnosis Original Research Orthopedics Osteogenesis Osteogenesis imperfecta Phenotypes Spine (lumbar) Vertebrae |
SummonAdditionalLinks | – databaseName: SpringerLink Journals (ICM) dbid: U2A link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LS8QwEB7WFcSL6K6P6ioRxINS6SNNm-OyuiyCHsSFvZUmTVDEVvZx8N87SR8iqwdvheZRZqaZL_lmJgAXeU5ZmFHpysjPXETEvpvhKmht2feVqVlko3wf2WRK72fRrANBe3RRvN00jKRdqNtcN-NtTOhP4nqUcpdtwKbBDsaSp8GwZQ4oq_hJH2flLJ41TOZvQ_z0RWsAc40ctT5nvAs7NVgkw0q7e9BRRQ_6wwI3yu-f5JLY8E17Lt6DrYeaJe9DdFvFz70uSKnJkzlRNzWYyNhkRK3mirwWJCPtJR1kVL4gCN-H6fjueTRx6-sRXBnGwdL1maZSixwxnfAyGfjai7VQXAqVM0lxJcs545zGOYIwJrkwqWcq0x7VEQ3QzR9AtygLdQQkDJTyhEyYDinN4ggVi4-JzEUupeK-A1eNoNKPqgpG2tY7tlJNUaqpkWrKHBg0okzrH2KRBp7JiEW0kjhw3r5GUzb8RFaocmXb8Ag3xmHowGGlgnY29Jqmc-zAdaOT78H__JTjf7U-ge3AGIfNNBxAdzlfqVOEHEtxZm3sC0kOymI priority: 102 providerName: Springer Nature |
Title | Diagnosis of Recurrent Fracture in a Pediatric Cohort |
URI | https://link.springer.com/article/10.1007/s00223-018-0449-6 https://www.ncbi.nlm.nih.gov/pubmed/29943187 https://www.proquest.com/docview/2058844318/abstract/ https://search.proquest.com/docview/2059552333 |
Volume | 103 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfR1ZS9xA-MMDxJfSesZamULpgzKYSSaTnSdZ7W4XpVLEhfUpzBXchyYeuw_99_1mcoiIfUrIOfm-L999AHyzlotUcUNNxhRFjZhRhVww0DJjzvcsClm-12Iy5ZezbLYCk64WxqdVdjwxMGpbG-8jRyPdl1SiuBucKu29AGZxevbwSP38KB9nbYdprMI6S1CtQMrOZ73pheygiVoyXIsU-ayLb8ahnSiKSDSpBzTmXFLxWkK9UTvfhEyDJBp_hA-tCkmGDc4_wYqrtmB7WKH5_Ocv-U5CUmfwlm_Bxq82dr4N2Y8mq27-TOqS3Hg_u-_MRMb-I5dPjswrokg_uoNc1Peomu_AdDy6vZjQdmgCNWmeLCgTJTeltqjp6ViZhJVxXmonjXZWGI78zUohJc8tqmbCSO0L0pwqY15mPEHhvwtrVV25fSBp4lyszUCUKecqzxDduDswVltjnGQRHHeAKh6a3hhF3wU5QLVAqBYeqoWI4LADZdH-Js_FC1Ij-NqfRgL3UQtVuXoZrpEZmstpGsFeg4L-bShL_c15BCcdTl4e_u5SDv6_lM-wmXhqCAWHh7C2eFq6L6h5LPRRIKojWB_-vLsa4fZ8dP37Bo9Ok-E_erjWIA |
link.rule.ids | 315,786,790,12083,21416,27957,27958,31754,31755,33779,33780,41116,41558,42185,42627,43345,43840,52146,52269,74102,74659 |
linkProvider | ProQuest |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LS8NAEB58gHoR38bnCuJBWchjs-meRKqlautBWugtJLsb7MGk2vbgv3d28xApeiukSZaZycw3b4BLpRgPEiapDL2EIiL2aIJa0Mqy52kzs8hW-b7w7pA9jcJRFXCbVmWVtU60iloV0sTI0Uk3LZVo7lq3kw9qtkaZ7Gq1QmMZVlkQMFPSF40ahwuVQJmr9PAEgkejOqvp2iGiaBjRkW5RlzFB-W-7tAA2FxKl1v50tmCzAo7kruT0NizpfAd273J0mt-_yBWxpZw2Rr4Da_0qY74L4X1ZSzeekiIjrya6buYxkY7pjpp_ajLOSUKahR2kXbwhIN-DYedh0O7SalUClUHkz6jHMyazVCG-S91E-l7mRlmqhUy14pKhVlOCC8EihYCMS5GaNjSdZC7LQuajyd-HlbzI9SGQwNfaTWWLZwFjSRQik_FnS6pUSamF58B1Tah4Uk7EiJvZx5aqMVI1NlSNuQMnNSnj6uOYxj-sdOCiuYxibXIVSa6Luf2PCNFJDgIHDkoWNG9DC2pujhy4qXny8_A_j3L0_1HOYb076Pfi3uPL8zFs-EYybMvhCazMPuf6FLHHLD2zAvYNyP3RPA |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1JS-xAEC5cQLyIu3HtB-JBaczS6UyfxG1Qnw4iT5hbSHpBDybqzBz891Z3OpGH6C2QdNJUVaq-6toA9pViPCmYpDKNCoqIOKIFakEny1Gkbc8il-U74FeP7GaYDn3-08inVbY60SlqVUt7Ro5Oui2pRHPXOzY-LeL-on_y-kbtBCkbafXjNKZhNmM8RQmfPbsc3D90MQXGm8hlhPsRPBu2Mc7QtRRFM4ludY-GjAnK_7dS36Dnt7Cps0b9RVjwMJKcNnxfgildLcPKaYUu9MsHOSAusdOdmC_D3J2Pn69AetFk1j2PSG3Igz1rt92ZSN_WSk3eNXmuSEG68R3kvH5CeL4Kj_3Lf-dX1A9OoDLJ4jGNuGHSlArRXhkWMo5MmJlSC1lqxSVDHacEF4JlCuEZl6K0RWm6MCEzKYsRAKzBTFVXegNIEmsdlrLHTcJYkaXIcrzsSVUqKbWIAjhsCZW_Nv0x8q4TsqNqjlTNLVVzHsB2S8rc_yqj_IuxAfzpbqOQ28hFUel64p4RKbrMSRLAesOC7mtoT-3iLICjlidfL_9xK5u_b2UP5lC68tvrwd8tmI-tYLj6w22YGb9P9A4CkXG56yXsE32B1t8 |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Diagnosis+of+Recurrent+Fracture+in+a+Pediatric+Cohort&rft.jtitle=Calcified+tissue+international&rft.au=Fiscaletti%2C+M&rft.au=Coorey%2C+C+P&rft.au=Biggin%2C+A&rft.au=Briody%2C+J&rft.date=2018-11-01&rft.pub=Springer+Nature+B.V&rft.issn=0171-967X&rft.eissn=1432-0827&rft.volume=103&rft.issue=5&rft.spage=529&rft.epage=539&rft_id=info:doi/10.1007%2Fs00223-018-0449-6&rft.externalDBID=HAS_PDF_LINK |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0171-967X&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0171-967X&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0171-967X&client=summon |