Treatment of advanced condylomata acuminata with semi-purified and purified human leukocyte interferon

Twelve patients with advanced condylomata acuminata were treated by systemic human leukocyte interferon (IFN) therapy. Semi-purified and purified preparations were both able to affect condylomatous growth. Treatment of the patients at various periods of their disease resulted in one complete remissi...

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Bibliographic Details
Published inActa oncologica Vol. 30; no. 3; p. 343
Main Authors Einhorn, N, Ling, P, Secher, D, Strander, H
Format Journal Article
LanguageEnglish
Published England 1991
Subjects
Adult
Condylomata Acuminata - drug therapy
Female
Humans
Interferon Type I - adverse effects
Interferon Type I - isolation & purification
Interferon Type I - therapeutic use
Middle Aged
Papillomaviridae
Vulvar Neoplasms - drug therapy
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Summary:Twelve patients with advanced condylomata acuminata were treated by systemic human leukocyte interferon (IFN) therapy. Semi-purified and purified preparations were both able to affect condylomatous growth. Treatment of the patients at various periods of their disease resulted in one complete remission, 6 partial remissions, 4 minimal responses while one case showed progressive disease. Side-effects were unexpectedly common in these advanced patients and 4 of them had to stop IFN treatment.
ISSN:0284-186X
DOI:10.3109/02841869109092383