Ionic probe attachment ionization mass spectrometry

A new ionization method that uses metal-complex-based ionization probes containing the 2,6-bis(oxazolinyl)pyridine (pybox) ligand is presented. This method was proven to effectively ionize large complex molecules, including biomolecules. The preparation of the charged probes and their application to...

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Bibliographic Details
Published inTetrahedron letters Vol. 50; no. 46; pp. 6252 - 6255
Main Authors Ito, Fumihiro, Nakamura, Tomoko, Yorita, Satoko, Danjo, Hiroshi, Yamaguchi, Kentaro
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 18.11.2009
Elsevier
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
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Summary:A new ionization method that uses metal-complex-based ionization probes containing the 2,6-bis(oxazolinyl)pyridine (pybox) ligand is presented. This method was proven to effectively ionize large complex molecules, including biomolecules. The preparation of the charged probes and their application to the ionization of biomolecules using cold-spray ionization mass spectrometry are shown.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2009.09.021