Hyperpigmentation in photo exposed patches of vitiligo following tacrolimus therapy

Vitiligo is an acquired pigmentary disorder, clinically characterized by depigmented macules caused by destruction of melanocytes in the affected skin. Half of all patients develop the disease in childhood and adolescence before the age of 20 years, making vitiligo an important skin disease of child...

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Bibliographic Details
Published inIndian Dermatology Online Journal Vol. 5; no. 2; pp. 164 - 166
Main Authors Sahni, Kanika, Gupta, Vishal, Khanna, Neena
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.04.2014
Medknow Publications & Media Pvt Ltd
Wolters Kluwer Medknow Publications
Subjects
Case Report
Hyperpigmentation
Skin
Tacrolimus
tacrolimus induced hyperpigmentation
vitiligo
vitiligo
tacrolimus induced hyperpigmentation
Hyperpigmentation
tacrolimus
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Summary:Vitiligo is an acquired pigmentary disorder, clinically characterized by depigmented macules caused by destruction of melanocytes in the affected skin. Half of all patients develop the disease in childhood and adolescence before the age of 20 years, making vitiligo an important skin disease of childhood. There are numerous studies in the literature that suggest the efficacy of topical tacrolimus in vitiligo, without serious adverse effects. We describe a case of vitiligo in a pediatric patient who developed hyperpigmentation in the periorbital lesions of vitiligo with the use of topical tacrolimus. To the best of our knowledge, this is only the second such reported occurrence in a patient with vitiligo.
ISSN:2229-5178
2249-5673
DOI:10.4103/2229-5178.131090