Clinical Application of Fast-Track Surgery with Chinese Medicine Treatment in the Devascularization Operation for Cirrhotic Portal Hypertension

• Published in: Chinese journal of integrative medicine Vol. 21; no. 10; pp. 784 - 790
• Main Author: 韦杨年 李年丰 蔡小勇 卢榜裕 黄飞 莫世发 张洪昌 王明栋 吴发胜
• Format: Journal Article
• Language: English
• Published: Beijing Chinese Association of Traditional and Western Medicine 01.10.2015
• Subjects: Adult; Aged; Anesthesia Recovery Period; Blood Loss, Surgical; Blood Transfusion; Chronic Disease; Clinical Experience; Esophageal and Gastric Varices - surgery; Esophageal and Gastric Varices - therapy; Female; Humans; Length of Stay; Liver Cirrhosis - complications; Male; Medicine; Medicine & Public Health; Medicine, Chinese Traditional; Middle Aged; Operative Time; Postoperative Complications; Postoperative Period; Quality of Life; Splenectomy; 中药治疗; 临床应用; 围手术期; 外科手术; 康复; 断流; 肝硬化; 门静脉; fast-track surgery; portal-azygous disconnection; Chinese medicine treatment; cirrhotic esophageal varices; splenectomy
• ISSN: 1672-0415; 1993-0402
• DOI: 10.1007/s11655-015-2317-9

ABSTRACT Objective： To investigate the clinical effect of fast-track surgery combined with Chinese medicine treatment in devascularization operation for cirrhotic esophageal varices. Methods： Seventy-two patients with cirrhotic esophageal varices were selected from January 2009 to June 2013, and randomly assigned to a conventional group and a fast-track group （fast-track surgery combined with Chinese medicine treatment） using a randomized digital table, 36 cases in each group. Operation and anesthesia recovery time, postoperative hospitalization and quality of life were recorded and compared between groups during the perioperative period. Results： Compared with the conventional group, the fast-track group had longer operation time （253.6±46.4 min vs. 220.6±51.0 min） and anesthesia recovery time （50.5 ± 15.9 rain vs. 23.5± 9.6 min; P〈0.01）; less bleeding （311.3±46.8 mL vs. 356.2 ± 57.5 mL; P〈0.01） and less transfusion （1932.3 ± 106.9 mL vs. 2045.6 ± 115.4 mL; P〈0.01）; as well as faster recovery of gastrointestinal function, shorter postoperative hospitalization and higher quality of life. There were no serious postoperative complications and no further bleeding occurred. Conclusion： Fast-track surgery combined with Chinese medicine treatment is a safe and feasible approach to accelerate the recovery of patients with cirrhotic portal hypertension in perioperative period of devascularization operation.