Catheter systems for intrathecal drug delivery

A prospective study of intrathecal catheter reliability was performed at Rush-Presbyterian-St. Luke's Medical Center. All 102 patients who had baclofen administered chronically for spasticity via an implanted drug pump were included. Sixty percent of the patients had no catheter complications;...

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Bibliographic Details
Published inJournal of neurosurgery Vol. 83; no. 2; p. 215
Main Authors Penn, R D, York, M M, Paice, J A
Format Journal Article
LanguageEnglish
Published United States 01.08.1995
Subjects
Adolescent
Adult
Aged
Baclofen - administration & dosage
Catheters, Indwelling - adverse effects
Child
Equipment Design
Equipment Failure
Female
Follow-Up Studies
Humans
Infusion Pumps, Implantable - adverse effects
Injections, Spinal - adverse effects
Injections, Spinal - instrumentation
Male
Middle Aged
Muscle Spasticity - drug therapy
Prospective Studies
Reproducibility of Results
Silicone Elastomers
Surface Properties
Survival Analysis
Titanium
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Summary:A prospective study of intrathecal catheter reliability was performed at Rush-Presbyterian-St. Luke's Medical Center. All 102 patients who had baclofen administered chronically for spasticity via an implanted drug pump were included. Sixty percent of the patients had no catheter complications; the remaining patients had one to five complications over their course of treatment. Survival analysis demonstrated a steady rate of malfunction up to 80 months, with the mean time to first failure recorded at 20 months. Kinks, holes, breaks, dislodgments, and disconnections were the most common complications. On the basis of their research the authors conclude that the thin-walled silastic catheter does not perform well and that larger, thick-walled catheters should be used.
ISSN:0022-3085
DOI:10.3171/jns.1995.83.2.0215