American Burn Association consensus conference to define sepsis and infection in burns

• Published in: Journal of burn care & research Vol. 28; no. 6; p. 776
• Main Authors: Greenhalgh, David G, Saffle, Jeffrey R, Holmes, 4th, James H, Gamelli, Richard L, Palmieri, Tina L, Horton, Jureta W, Tompkins, Ronald G, Traber, Daniel L, Mozingo, David W, Deitch, Edwin A, Goodwin, Cleon W, Herndon, David N, Gallagher, James J, Sanford, Art P, Jeng, James C, Ahrenholz, David H, Neely, Alice N, O'Mara, Michael S, Wolf, Steven E, Purdue, Gary F, Garner, Warren L, Yowler, Charles J, Latenser, Barbara A
• Format: Journal Article
• Language: English
• Published: England 01.11.2007
• Subjects: Burns - complications; Burns - microbiology; Catheterization, Central Venous - adverse effects; Humans; Infection - diagnosis; Multiple Organ Failure - diagnosis; Pneumonia - diagnosis; Sepsis - diagnosis; Severity of Illness Index; Smoke Inhalation Injury - diagnosis; Systemic Inflammatory Response Syndrome - diagnosis
• ISSN: 1559-047X
• DOI: 10.1097/bcr.0b013e3181599bc9

Because of their extensive wounds, burn patients are chronically exposed to inflammatory mediators. Thus, burn patients, by definition, already have "systemic inflammatory response syndrome." Current definitions for sepsis and infection have many criteria (fever, tachycardia, tachypnea, leukocytosis) that are routinely found in patients with extensive burns, making these current definitions less applicable to the burn population. Experts in burn care and research, all members of the American Burn Association, were asked to review the literature and prepare a potential definition on one topic related to sepsis or infection in burn patients. On January 20, 2007, the participants met in Tucson, Arizona to develop consensus for these definitions. After review of the definitions, a summary of the proceedings was prepared. The goal of the consensus conference was to develop and publish standardized definitions for sepsis and infection-related diagnoses in the burn population. Standardized definitions will improve the capability of performing more meaningful multicenter trials among burn centers.