Compression of the brachial artery in vivo

Stiffening of the brachial artery is implicated in pseudo-hypertension. To date, a reliable clinical predictor of the condition has not been developed. This paper describes the development of prototype instrumentation and methodology for measurement of the brachial artery transmural pressure/cross-s...

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Bibliographic Details
Published inPhysiological measurement Vol. 25; no. 2; pp. 553 - 564
Main Authors Foran, Timothy G, Sheahan, Noirin F
Format Journal Article
LanguageEnglish
Published England IOP Publishing 01.04.2004
Subjects
Blood Pressure - physiology
Blood Pressure Determination - instrumentation
Blood Pressure Determination - methods
Brachial Artery - physiology
Humans
Regional Blood Flow - physiology
Vasodilation - physiology
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Summary:Stiffening of the brachial artery is implicated in pseudo-hypertension. To date, a reliable clinical predictor of the condition has not been developed. This paper describes the development of prototype instrumentation and methodology for measurement of the brachial artery transmural pressure/cross-sectional area relationship in vivo. The methodology has been validated using a model of an arm and a thin-walled rubber tube. Application of the technique to a healthy subject shows that the technique is viable and gives good reproducibility. Closure of the brachial artery with reducing transmural pressure is observed and recorded. The new technique has some important advantages over existing methodologies.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0967-3334
1361-6579
DOI:10.1088/0967-3334/25/2/012