Sickle cell disease and readmissions rates after lower extremity arthroplasty: a multistate analysis 2007-2014

To compare readmission rates between patients with sickle cell disease (SCD) and non-sickle cell disease undergoing total hip and knee arthroplasty (THA and TKA). Identified adult patients who underwent THA or TKA from 2007 to 2014 in California, Florida, New York, Maryland and Kentucky using a mult...

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Published inJournal of comparative effectiveness research Vol. 8; no. 6; pp. 403 - 422
Main Authors Chen, Yuefan, White, Robert S, Tangel, Virginia, Noori, Selaiman A, Gaber-Baylis, Licia K, Mehta, Neel D, Pryor, Kane O
Format Journal Article
LanguageEnglish
Published England Future Medicine Ltd 01.04.2019
Subjects
hematology
Joint surgery
Mortality
observational research
Observational studies
outcomes research
Sickle cell disease
observational research
hematology
outcomes research
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Summary:To compare readmission rates between patients with sickle cell disease (SCD) and non-sickle cell disease undergoing total hip and knee arthroplasty (THA and TKA). Identified adult patients who underwent THA or TKA from 2007 to 2014 in California, Florida, New York, Maryland and Kentucky using a multistate database. Outcomes were 30- and 90-day readmission rates, mortality, complications, length of stay and hospital charges. Logistic regression models were used for analysis. Compared with non-sickle cell disease patients following TKA and THA, SCD patients had higher odds of 30- (odds ratio [OR]: 3.79) and 90-day readmissions (OR: 4.15), mortality (OR: 6.54), more complications, longer length of stay, and higher total charges. Following TKA and THA, SCD is associated with higher readmissions and worse outcomes.
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ISSN:2042-6305
2042-6313
DOI:10.2217/cer-2018-0098