The Malaysian genus Calophyllum (Calophyllaceae): a review on its phytochemistry and pharmacological activities

Genus Calophyllum from the family of Calophyllaceae is an evergreen broad-leaved tree that is endemic to Southeast Asia, especially Malaysia. They have been reported for various ethnomedicinal uses in traditional medicine. Previous studies of Malaysian Calophyllum species revealed them to be a rich...

Full description

Saved in:
Bibliographic Details
Published inNatural product research Vol. 36; no. 17; pp. 4569 - 4579
Main Authors Zailan, Ahmad Alif Danial, Karunakaran, Thiruventhan, Abu Bakar, Mohamad Hafizi, Mian, Vivien Jong Yi
Format Journal Article
LanguageEnglish
Published Abingdon Taylor & Francis 01.09.2022
Taylor & Francis Ltd
Subjects
bioactivity
Calophyllaceae
Calophyllum
Coumarin
ethnomedicinal
Evergreen trees
HIV
Human immunodeficiency virus
Pharmacology
phytochemical
Species
Terpenes
Malaysia
Online AccessGet full text

Cover

More Information
Summary:Genus Calophyllum from the family of Calophyllaceae is an evergreen broad-leaved tree that is endemic to Southeast Asia, especially Malaysia. They have been reported for various ethnomedicinal uses in traditional medicine. Previous studies of Malaysian Calophyllum species revealed them to be a rich source of bioactive phytoconstituents such as xanthones, coumarins, terpenoids, and chromanone acids. To date, the extracts and compounds from Malaysian Calophyllum species have shown a broad spectrum of pharmacological activities. For example, calanolide A, a coumarin isolated from Malaysian C. lanigerum, has now reached clinical development to become an anti-HIV drug. This article presents an overview of the significant phytochemical and pharmacological activities of Malaysian Calophyllum species to aid researchers in further discovery of potential benefits of various species of this genus.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2021.1982936