Recurrent transverse myelitis associates with anti-Ro (SSA) autoantibodies

Transverse myelitis (TM) is an idiopathic inflammatory disorder of the spinal cord. The authors observed cases of recurrent TM in patients where anti-Ro (SSA) antibodies were present and therefore performed a case-control study to examine the frequency of anti-Ro autoantibodies in patients with recu...

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Bibliographic Details
Published inNeurology Vol. 62; no. 1; p. 147
Main Authors Hummers, L K, Krishnan, C, Casciola-Rosen, L, Rosen, A, Morris, S, Mahoney, J A, Kerr, D A, Wigley, F M
Format Journal Article
LanguageEnglish
Published United States 13.01.2004
Subjects
Adolescent
Adult
Age of Onset
Aged
Antibodies, Antinuclear - blood
Autoantibodies - blood
Autoantigens
Case-Control Studies
Female
Follow-Up Studies
Humans
Male
Middle Aged
Myelitis, Transverse - diagnosis
Myelitis, Transverse - immunology
Recurrence
Retrospective Studies
Ribonucleoproteins - immunology
RNA, Small Cytoplasmic
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Summary:Transverse myelitis (TM) is an idiopathic inflammatory disorder of the spinal cord. The authors observed cases of recurrent TM in patients where anti-Ro (SSA) antibodies were present and therefore performed a case-control study to examine the frequency of anti-Ro autoantibodies in patients with recurrent TM and control subjects. Antibodies to 52-kd Ro were demonstrated in 77% of cases (10/13) compared with only 33% of control subjects (4/12).
ISSN:1526-632X
DOI:10.1212/01.WNL.0000101715.32569.1A