TTV and other anelloviruses: The astonishingly wide spread of a viral infection

The broad family of viruses known as anelloviruses (AV) infects both humans and numerous animal species. They have a tiny, covalently closed single-stranded DNA genome and the astonishing capacity to infect a very high percentage of healthy and ill people with chronic infections that could last a li...

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Published inAspects of molecular medicine Vol. 1; p. None
Main Authors Spezia, Pietro Giorgio, Focosi, Daniele, Baj, Andreina, Novazzi, Federica, Ferrante, Francesca Drago, Carletti, Fabrizio, Minosse, Claudia, Matusali, Giulia, Maggi, Fabrizio
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 2023
Elsevier
Subjects
Anellovirus
Immune system
TTMDV
TTMV
TTV
Virome
TTMDV
Virome
TTMV
TTV
Anellovirus
Immune system
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Summary:The broad family of viruses known as anelloviruses (AV) infects both humans and numerous animal species. They have a tiny, covalently closed single-stranded DNA genome and the astonishing capacity to infect a very high percentage of healthy and ill people with chronic infections that could last a lifetime. AV, and particularly the prototype Torquetenovirus, have established a successful interaction with the host's immune system and the rate at which they replicate is a gauge to measure overall immune function, even though many aspects of their life cycle and pathogenesis are still poorly understood.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ISSN:2949-6888
2949-6888
DOI:10.1016/j.amolm.2023.100006