RELATIONSHIP BETWEEN LYMPHOCYTE SUBSETS OF THE PERIPHERAL BLOOD AND NOISE INDUCED HEARING LOSS

Biochemical examination and two-color flow cytometric analysis of lymphocyte subsets of the peripheral blood were carried out in 107 healthy males working in high noise environments. The level of hearing disorder was compared with these results. By audiometry at six frequency levels, 51 of the 107 h...

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Published inSangyo Igaku Vol. 35; no. 1; pp. 3 - 6
Main Authors KOMORI, Mayumi, MIWA, Masato, MORITA, Mayumi, NIIYA, Yoshihide, HAMAMATSU, Akio, NIWA, Tamami, KOMORI, Yoshitaka, SARAI, Susumu, IWATA, Shigenobu
Format Journal Article
LanguageJapanese
Published Tokyo Japan Society for Occupational Health 1993
Japan Association of Industrial Health
Subjects
Adult
Hearing Loss, Noise-Induced - immunology
Humans
lymphocyte subset
Lymphocyte Subsets - immunology
Male
Middle Aged
noise induced hearing loss
Occupational Exposure
steel mill worker
two-color flow cytometry
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Summary:Biochemical examination and two-color flow cytometric analysis of lymphocyte subsets of the peripheral blood were carried out in 107 healthy males working in high noise environments. The level of hearing disorder was compared with these results. By audiometry at six frequency levels, 51 of the 107 healthy males showed hearing loss. Their mean value of hearing ability was 30 dB and/or above. Among the peripheral lymphocyte subsets, helper T cells of CD4+CD45R- were significantly increased and the CD4/CD8 ratio tended to be elevated. CD20 that indicate B cells were reduced. These results suggested a relationship between susceptibility to acoustic trauma and cell-mediated immunity.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0047-1879
1881-1302
DOI:10.1539/joh1959.35.3