Ivermectin toxicosis in a kitten

A 4-month-old female kitten developed generalized ataxia, mild tremors, weakness, incoordination, and miosis after receiving an injection of ivermectin (0.3 mg/kg of body weight, SC) for treatment of ear mite infestation. The kitten became comatose within 12 hours, and despite supportive treatment,...

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Bibliographic Details
Published inJournal of the American Veterinary Medical Association Vol. 205; no. 4; p. 584
Main Authors Lewis, D.T, Merchant, S.R, Neer, T.M
Format Journal Article
LanguageEnglish
Published United States 15.08.1994
Subjects
ADVERSE EFFECTS
Age Factors
Animals
APPLICATION METHODS
CASE STUDIES
Cat Diseases - chemically induced
Cat Diseases - drug therapy
Cats
CHATON
DRUG THERAPY
EFECTOS SECUNDARIOS
EFFET SECONDAIRE
ESTUDIOS DE CASOS PRACTICOS
ETUDE DE CAS
Fatal Outcome
Female
GATITO
Injections, Subcutaneous - veterinary
IVERMECTIN
Ivermectin - administration & dosage
Ivermectin - poisoning
Ivermectin - therapeutic use
IVERMECTINA
IVERMECTINE
KITTENS
METHODE D'APPLICATION
METODOS DE APLICACION
Mite Infestations - drug therapy
Mite Infestations - veterinary
OTODECTES CYNOTIS
PARENTERAL ADMINISTRATION
SIDE EFFECTS
TERAPEUTICA MEDICAMENTOSA
THERAPEUTIQUE MEDICAMENTEUSE
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Summary:A 4-month-old female kitten developed generalized ataxia, mild tremors, weakness, incoordination, and miosis after receiving an injection of ivermectin (0.3 mg/kg of body weight, SC) for treatment of ear mite infestation. The kitten became comatose within 12 hours, and despite supportive treatment, died 7 days after administration of ivermectin. Caution should be exercised when this drug is administered parenterally to kittens.
Bibliography:L74
L72
9503041
ISSN:0003-1488
1943-569X
DOI:10.2460/javma.1994.205.04.584