Axon guidance: GTPases help axons reach their targets

During development and regeneration of the nervous system, axons must correctly navigate to their specific targets through a complex molecular environment. Recent work has shed light on how GTPases of the Ras family are involved in transducing extracellular signals into responses that lead to direct...

Full description

Saved in:
Bibliographic Details
Published inCurrent biology Vol. 8; no. 3; pp. R80 - R82
Main Authors Gallo, Gianluca, Letourneau, Paul C
Format Journal Article
LanguageEnglish
Published England Elsevier Inc 29.01.1998
Subjects
Animals
Axons - physiology
Caenorhabditis elegans - embryology
Caenorhabditis elegans - genetics
cdc42 GTP-Binding Protein
Cell Cycle Proteins - physiology
Dendrites - physiology
Enzyme Activation
GTP Phosphohydrolases - physiology
GTP-Binding Proteins - physiology
Multigene Family
Nervous System - growth & development
Neuroblastoma - pathology
rac GTP-Binding Proteins
rho GTP-Binding Proteins
Signal Transduction - physiology
Tumor Cells, Cultured
Online AccessGet full text

Cover

More Information
Summary:During development and regeneration of the nervous system, axons must correctly navigate to their specific targets through a complex molecular environment. Recent work has shed light on how GTPases of the Ras family are involved in transducing extracellular signals into responses that lead to directed neurite outgrowth.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-Review-3
content type line 23
ObjectType-Feature-3
ObjectType-Review-1
ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(98)70051-X