Microwave ablation for recurrent primary hyperparathyroidism in four patients with multiple endocrine neoplasia type 1: a case series report

• Published in: International journal of hyperthermia Vol. 41; no. 1; p. 2308056
• Main Authors: Tan, Jie, Zhang, Yuzhi, Han, Xue, Fan, Yaofu, Xu, Juan, Chen, Guofang, Liu, Chao, Xu, Shuhang
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis Group 2024
• Subjects: case series report; Humans; Hyperparathyroidism, Primary - diagnostic imaging; Hyperparathyroidism, Primary - surgery; Microwave ablation; Microwaves - therapeutic use; multiple endocrine neoplasia; Multiple Endocrine Neoplasia Type 1 - complications; Multiple Endocrine Neoplasia Type 1 - surgery; Parathyroidectomy; primary hyperparathyroidism; recurrence; Treatment Outcome; recurrence; Microwave ablation; case series report; primary hyperparathyroidism; multiple endocrine neoplasia
• ISSN: 0265-6736; 1464-5157
• DOI: 10.1080/02656736.2024.2308056

Multiple endocrine neoplasia type 1 (MEN1), a rare tumor syndrome, is inherited in an autosomal dominant pattern, mainly manifested as primary hyperparathyroidism (PHPT). Surgery is preferred for patients with MEN1 and PHPT. Thermal ablation has been widely applied for PHPT but rarely for postoperative recurrent PHPT in MEN1 patients. Based on a series of cases, we aimed to investigate the clinical efficacy and safety of ultrasound-guided percutaneous microwave ablation in the treatment of MEN1 patients with postoperative recurrence of PHPT.