Antimicrobial peptides isolated from insects and their potential applications

• Published in: Journal of Asia-Pacific entomology Vol. 25; no. 2; pp. 101892 - 22
• Main Authors: Azmiera, N., Krasilnikova, A., Sahudin, S., Al-Talib, H., Heo, C.C.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.06.2022; 한국응용곤충학회
• Subjects: Antimicrobial drugs; Antimicrobial peptides; antimicrobial properties; Blattodea; Coleoptera; Diptera; drug therapy; entomology; Hemiptera; Hymenoptera; Insects; Lepidoptera; Mechanism of antimicrobial action; Microorganisms; Odonata; 농학; Antimicrobial drugs; Microorganisms; Mechanism of antimicrobial action; Insects; Antimicrobial peptides
• ISSN: 1226-8615; 1876-7990
• DOI: 10.1016/j.aspen.2022.101892

[Display omitted] •The recent advances of antimicrobial peptides isolated from insects were reviewed.•Characterization and mechanisms of AMPs from various insect Orders were summarized.•The most studied insect Orders were Hymenoptera, followed by Diptera and Coleoptera.•A list of AMPs, methods for characterization, and bacteria tested were catalogued.•A pictorial summary of the procedures for AMPs extraction and isolation was provided. Antimicrobial peptides (AMPs) in insects have the potential to be developed as chemotherapy agents against numerous microbial species. This article reviewed the existing knowledge of what have been focused so far on published materials related to AMPs isolated from insects. Previous studies were focused on peptide characterization and the mechanism pathways of different AMPs from a variety of insect Orders. Most studied insect Orders are as follows: Hymenoptera (50%), Diptera (17%), Coleoptera (13%), Lepidoptera (10%), Hemiptera (5%), Blattodea (3%) and Odonata (2%). Dozens of new AMPs have been extracted from insects recently. However, more studies in vivo and in vitro are necessary to fully understand their effect and the mechanisms of antimicrobial action to utilize their promising potential in cosmetic and pharmaceutical industries.