Nodule and Eminence on Frenulum Labii Superioris. Diagnostic Markers for Metastatic Colorectal Cancer

• Published in: Chinese journal of integrative medicine Vol. 20; no. 6; pp. 416 - 419
• Main Author: 曹蕊 王丽萍 池嘉栋 吴雄志
• Format: Journal Article
• Language: English
• Published: Heidelberg Chinese Association of Traditional and Western Medicine 01.06.2014
• Subjects: Acupuncture Points; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms - diagnosis; Colorectal Neoplasms - pathology; Female; Humans; Male; Medicine; Medicine & Public Health; Middle Aged; Neoplasm Metastasis - diagnosis; Neoplasm Metastasis - pathology; Original Article; 上唇; 包皮; 标志物; 经络学说; 结直肠癌; 结节; 诊断; 转移性; recurrence; colorectal cancer; metastasis; frenulum labii superioris
• ISSN: 1672-0415; 1993-0402; 1993-0402
• DOI: 10.1007/s11655-014-1681-1

Objective： To determine whether the nodule and eminence on the frenulum labii superioris, location of Yinjiao （DU28） according to the meridian theory, could be used to prognosticate the recurrence of patients with colorectal cancer. Methods： The data of 101 patients with colorectal cancer in Tianjin Medical University Cancer Institute and Hospital from May 2011 to November 2011 was analyzed. The photos of all patients＇ frenulum labii superioris were taken. Nodule and eminence on frenulum labii superioris were the positive standard. Biopsy and pathological testing for the nodule were carried out on one patient with large nodule on frenulum labii superioris. Results： Patients with positive frenulum labii superioris had a higher risk of recurrence and/or metastasis than patients with negative frenulum labii superioris. There were no significant differences in diagnosis of recurrence and/or metastasis between the status of frenulum labii superioris and the traditional diagnostic criteria （P=0.238）. The Kappa was 0.606 （P〈0.001）. The sensitivity was 76.0% and the specificity was 85.4%. The pathological report demonstrated that the nodule on frenulum labii superioris was mucosal excrescence with normal structure. Conclusion： Nodule and eminence on frenulum labii superioris are potential diagnostic markers for metastatic colorectal cancer.