Xerosis in hypothyroidism: a potential role for the use of topical thyroid hormone in euthyroid patients

Xerosis is an extraordinarily common problem in dermatology. Despite the knowledge of well recognized aggravating factors, its etiology is an enigma, and the management of the condition is often suboptimal. Dry skin may be a manifestation of hypothyroidism. The nature of this association is reviewed...

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Published inMedical hypotheses Vol. 57; no. 6; pp. 736 - 739
Main Authors Heymann, W.R., Gans, E.H., Manders, S.M., Green, J.J., Haimowitz, J.E.
Format Journal Article
LanguageEnglish
Published Kidlington Elsevier Ltd 01.12.2001
Elsevier
Subjects
Administration, Topical
Biological and medical sciences
Endocrinopathies
Humans
Hypothyroidism - complications
Medical sciences
Models, Biological
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Skin Diseases - drug therapy
Skin Diseases - etiology
Thyroid Hormones - administration & dosage
Thyroid. Thyroid axis (diseases)
Endocrinopathy
Human
Pathophysiology
Treatment efficiency
Thyroid diseases
Keratinization
Conjunctiva disease
Xerosis
Hypothyroidism
Route of administration
Eye disease
Concomitant disease
Chemotherapy
Treatment
Thyroid hormone
Topical administration
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Summary:Xerosis is an extraordinarily common problem in dermatology. Despite the knowledge of well recognized aggravating factors, its etiology is an enigma, and the management of the condition is often suboptimal. Dry skin may be a manifestation of hypothyroidism. The nature of this association is reviewed, culminating in the speculation that topical thyroid hormone may represent a useful modality in euthyroid patients with xerosis or other disorders of keratinization.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0306-9877
1532-2777
DOI:10.1054/mehy.2001.1448