SARS-CoV-2 antibodies in adolescents living with perinatally acquired HIV

Data on children and adolescents with HIV and coronavirus disease 2019 (COVID-19) co-infection are limited. Clinical and antibody data related to COVID-19 infection in adolescents living with perinatally acquired HIV (ALPHIV) and originally enrolled in the Children with HIV Early Antiretroviral Ther...

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Bibliographic Details
Published inSouthern African journal of infectious diseases Vol. 39; no. 1; pp. 579 - e3
Main Authors Frigati, Lisa, Greybe, Leonore, Barnabas, Shaun, Cotton, Mark, Rabie, Helena
Format Journal Article
LanguageEnglish
Published South Africa African Online Scientific Information Systems (Pty) Ltd t/a AOSIS 2024
AOSIS
Subjects
adolescent hiv
adolescents
Analysis
Antiviral agents
Brief Report
Children
Coronaviruses
covid-19
Diseases
HIV (Viruses)
Medical research
Medicine, Experimental
perinatal hiv
sars-cov2 antibodies
Vaccination
South Africa
COVID-19
perinatal HIV
adolescent HIV
SARS-CoV2 antibodies
adolescents
vaccination
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Summary:Data on children and adolescents with HIV and coronavirus disease 2019 (COVID-19) co-infection are limited. Clinical and antibody data related to COVID-19 infection in adolescents living with perinatally acquired HIV (ALPHIV) and originally enrolled in the Children with HIV Early Antiretroviral Therapy (CHER) study were collected. We present a descriptive analysis of 53 ALPHIV who were tested for anti-SARS-CoV-2 antibodies. Just over half (53%) of the adolescents tested had positive anti-SARS-CoV-2 antibodies with only one participant describing a prior history of possible symptomatic infection. The study contributes to the understanding of SARS-CoV-2 infection and vaccination practices in HIV-positive adolescents.
ISSN:2312-0053
2313-1810
DOI:10.4102/sajid.v39i1.579