Selective sensing of DNA and live/dead cells and histological imaging based on a perylene derivative

A mannose-modified perylene monoimide derivative PMI-Man was developed, which shows highly selective binding to double-stranded DNA molecules, potent live/dead cell imaging, and histological imaging via both confocal and light microscopies. This approach can be used to develop a universal colorful s...

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 57; no. 22; pp. 2776 - 2779
Main Authors Wang, Jun-Fang, Zhao, Chun-Miao, Yang, Jian-Xing, He, Xu, Li, Xiao-Liu, Li, Jin-Mei, Wang, Ke-Rang
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 16.03.2021
Subjects
DNA
histology
Human tissues
humans
Imaging
Mannose
Selective binding
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Summary:A mannose-modified perylene monoimide derivative PMI-Man was developed, which shows highly selective binding to double-stranded DNA molecules, potent live/dead cell imaging, and histological imaging via both confocal and light microscopies. This approach can be used to develop a universal colorful staining method for human tissues for both confocal and light microscopies. Highly selective binding to double-stranded DNA molecules, potent live/dead cell imaging, and histological imaging using both confocal and light microscopies based on a perylene monoimide derivative were developed.
Bibliography:10.1039/d1cc00145k
Electronic supplementary information (ESI) available: Materials, additional figures and methods used in the synthesis and characterization of the compounds. See DOI
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ISSN:1359-7345
1364-548X
1364-548X
DOI:10.1039/d1cc00145k