Large-volume multi-tined expandable RF ablation in pig livers: comparison of 2D and volumetric measurements of the ablation zone

• Published in: European radiology Vol. 20; no. 5; pp. 1073 - 1078
• Main Authors: Bangard, Christopher, Rösgen, Silvia, Wahba, Roger, Wiemker, Rafael, Hellmich, Martin, Reiter, Hannah, Fischer, Jürgen H., Stippel, Dirk L., Lackner, Klaus J.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.05.2010; Springer Nature B.V
• Subjects: Algorithms; Animals; Catheter Ablation - instrumentation; Contrast Media; Diagnostic Radiology; Electrodes; Imaging; Imaging, Three-Dimensional; Internal Medicine; Interventional; Interventional Radiology; Liver - diagnostic imaging; Liver - surgery; Male; Medicine; Medicine & Public Health; Neuroradiology; Radiographic Image Interpretation, Computer-Assisted; Radiology; Sus scrofa; Tomography, X-Ray Computed - methods; Ultrasound; Radiofrequency ablation; 3D; 2D; Pig liver; Computed tomography; Volume
• ISSN: 0938-7994; 1432-1084
• DOI: 10.1007/s00330-009-1639-4

Objectives To compare two-dimensional (2D) and three-dimensional (3D) computed tomography (CT) measurements of ablation zones (AZs) related to the shaft of two different large-volume monopolar multi-tined expandable electrodes. Methods Percutaneous radiofrequency (RF) ablation was performed in 12 pigs (81.6 ± 7.8 kg) using two electrodes (LeVeen 5 cm, Rita XL 5 cm; n  = 6 in each group). Contrast-enhanced CT with the electrode shaft in place evaluated the AZ. The largest sphere centred on the electrode shaft within the AZ was calculated (1) based on the 2D axial CT image in the plane of the shaft assuming rotational symmetry of the AZ and (2) using prototype software and the 3D volume data of the AZ measured with CT. Results The mean largest diameter of a sphere centred on the electrode shaft was always smaller using the 3D data of the AZ than using 2D CT measurements assuming rotational symmetry of the AZ (3D vs 2D): LeVeen 18.2 ± 4.8 mm; 24.5 ± 3.1 mm; p  = 0.001; Rita XL 20.0 ± 3.7 mm; 28.8 ± 4.9 mm; p  = 0.0002. All AZ showed indentations around the tines. Conclusions Two-dimensional CT measurements assuming rotational symmetry of the AZ overestimate the largest ablated sphere centred on the electrode shaft compared with 3D CT measurements.