Idiopathic Granulomatous Mastitis as a Benign Condition Mimicking Inflammatory Breast Cancer: Current Status, Knowledge Gaps and Rationale for the GRAMAREG Study (EUBREAST-15)

• Published in: Cancers Vol. 16; no. 19; p. 3387
• Main Authors: Krawczyk, Natalia, Kühn, Thorsten, Ditsch, Nina, Hartmann, Steffi, Gentilini, Oreste Davide, Lebeau, Annette, de Boniface, Jana, Hahn, Markus, Çakmak, Güldeniz Karadeniz, Alipour, Sadaf, Bjelic-Radisic, Vesna, Kolberg, Hans-Christian, Reimer, Toralf, Gasparri, Maria Luisa, Tauber, Nikolas, Neubacher, Melissa, Banys-Paluchowski, Maggie
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 03.10.2024; MDPI
• Subjects: Antibiotics; Bacteria; Biopsy; Birth control; Breast cancer; Breast feeding; Breastfeeding & lactation; Cancer; Care and treatment; Case reports; Contraceptives; Development and progression; Diagnosis; Diagnosis, Differential; Disease; Drug therapy; Emotions; Etiology; Evidence-based medicine; Gram-positive bacteria; Granulomas; Health aspects; Immunoglobulin M; Immunosuppressive agents; Infection; Infections; Inflammation; Inflammatory breast cancer; Mastitis; Menopause; Neutrophils; Nonsteroidal anti-inflammatory drugs; Oncology, Experimental; Pain; Patients; Pregnancy; Prolactin; Review; Risk factors; Sarcoidosis; Smoking; Steroid hormones; Steroids; Surgery; Tuberculosis; Germany; Asia; Europe; methotrexate; steroids; breast inflammation; idiopathic granulomatous mastitis; immunosuppressants; surgery

Idiopathic granulomatous mastitis (IGM) is a rare, benign inflammatory breast condition often mistaken for inflammatory breast cancer and, therefore, requires a biopsy for accurate diagnosis. Although not cancerous, IGM can cause emotional distress because of severe pain and ensuing breast deformity...