Correlation between Ion Composition of Oligomineral Water and Calcium Oxalate Crystal Formation

The ion content of drinking water might be associated with urinary stone formation, representing a keystone of conservative nephrolithiasis management. However, the effects of specific ions on calcium oxalate crystal formation and their mechanism of action are still highly controversial. We report a...

Full description

Saved in:
Bibliographic Details
Published inCrystals (Basel) Vol. 11; no. 12; p. 1507
Main Authors Rossi, Manuela, Barone, Biagio, Di Domenico, Dante, Esposito, Rodolfo, Fabozzi, Antonio, D’Errico, Gerardino, Prezioso, Domenico
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.12.2021
Subjects
Aqueous solutions
Calcium
calcium oxalate
Chloride
Composition
Crystal growth
Drinking water
gravimetry
Interfacial energy
ion composition
Kidney stones
Metabolism
Microscopy
Mineral water
optical microscopy
Polyethylene terephthalate
Sodium
Software
Statistical analysis
United States > US
Germany
Online AccessGet full text

Cover

More Information
Summary:The ion content of drinking water might be associated with urinary stone formation, representing a keystone of conservative nephrolithiasis management. However, the effects of specific ions on calcium oxalate crystal formation and their mechanism of action are still highly controversial. We report an investigation of the effects of oligomineral waters with similar total salt amount but different ion composition on calcium oxalate (CaOx) precipitation in vitro, combining gravimetric and microscopic assays. The results suggest that the “collective” physicochemical properties of the aqueous medium, deriving from the ion combination rather than from a single ionic species, are of importance. Particularly, the ability of ions to strengthen/weaken the aqueous medium structure determines an increase/decrease in the interfacial energy, modulating the formation and growth of CaOx crystals.
ISSN:2073-4352
2073-4352
DOI:10.3390/cryst11121507