Early removal of a permanent catheter during the acute management of the unstable pediatric hemato-oncology patient with suspected catheter-related bloodstream infection: a multi-disciplinary survey and review of the literature

• Published in: European journal of pediatrics Vol. 182; no. 2; pp. 795 - 802
• Main Authors: Cohen, Neta, Rosenberg, Tom, Rimon, Ayelet, Friedman, Shirley
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2023; Springer Nature B.V
• Subjects: Bacteremia - diagnosis; Bacteremia - etiology; Bacteremia - therapy; Catheter-Related Infections - diagnosis; Catheter-Related Infections - therapy; Catheterization, Central Venous - adverse effects; Catheters; Central Venous Catheters - adverse effects; Child; Emergency medical care; Humans; Intravenous administration; Literature reviews; Medical treatment; Medicine; Medicine & Public Health; Neoplasms; Nosocomial infections; Oncology; Patients; Pediatrics; Physicians; Sepsis; Surveys; Hemodynamic instability; Hemato-oncology patients; Suspected catheter-related bloodstream infections (CRBSI); Pediatric patients; Permanent central catheter removal
• ISSN: 1432-1076; 0340-6199; 1432-1076
• DOI: 10.1007/s00431-022-04747-7

There are no guidelines for the optimal manner and timing of permanent central catheter removal in the hemodynamically unstable pediatric hemato-oncology patient with suspected catheter-related bloodstream infections (CRBSI). Our goals were to examine current practices of permanent central catheter management and choice of removal in the hemodynamically unstable pediatric patient with suspected CRBSI among practitioners in diverse subspecialties. We performed a literature review on the subject, and conducted a multi-disciplinary survey included pediatric oncologists, pediatric emergency medicine physicians, and pediatric intensive care physicians whom we queried about their choice of permanent central catheter management and removal while treating the hemodynamically unstable pediatric patient with suspected CRBSI. Most of the 78 responders ( n  = 47, 59%) preferred to utilize the existing permanent central catheter for initial intravenous access rather than an alternative access. There were no significant differences between physician subspecialties ( p  = 0.29) or training levels ( p  = 0.14). Significantly more pediatric emergency medicine physicians preferred not to remove the permanent central catheter at any time point compared to the pediatric hemato-oncologists, who preferred to remove it at some point during the acute presentation (44.4% vs. 9.4%, respectively, p  = 0.02). Conclusion : Our study findings reflect the need for uniform guidelines on permanent central catheter use and indications for its removal in the hemodynamically unstable pediatric patient. We suggest that permanent central catheter removal should be urgently considered in a deteriorating patient who failed to be stabilized with medical treatment. What is Known: •  There are no guidelines for the optimal choice and timing of permanent central catheter removal in the hemodynamically unstable pediatric hemato-oncology patient with suspected catheter-related bloodstream infection (CRBSI). What is New: •  We found variations in practices among pediatricians from diverse subspecialties and conflicting data in the literature. •  There is a need for prospective studies to provide uniform guidelines for optimal management of suspected CRBSI in the hemodynamically unstable pediatric patient.