Magnetic bead manipulation in a sub-microliter fluid volume applicable for biosensing

Magnetic actuation principles using superparamagnetic beads suspended in a fluid are studied in this paper. An experimental setup containing a sub-microliter fluid volume surrounded by four miniaturized electromagnets was designed and fabricated. On the basis of optical velocity measurements, the in...

Full description

Saved in:
Bibliographic Details
Published inMicrofluidics and nanofluidics Vol. 3; no. 2; pp. 141 - 149
Main Authors Derks, R. J. S., Dietzel, A., Wimberger-Friedl, R., Prins, M. W. J.
Format Journal Article
LanguageEnglish
Published Heidelberg Springer Nature B.V 01.04.2007
Subjects
Fluids
Manipulation
Online AccessGet full text

Cover

More Information
Summary:Magnetic actuation principles using superparamagnetic beads suspended in a fluid are studied in this paper. An experimental setup containing a sub-microliter fluid volume surrounded by four miniaturized electromagnets was designed and fabricated. On the basis of optical velocity measurements, the induced behavior of single beads and ordered chains was analyzed and compared to a theoretical model. This research can be used to develop new techniques for accelerated transportation in lab-on-a-chip bio-assays.[PUBLICATION ABSTRACT]
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1613-4982
1613-4990
DOI:10.1007/s10404-006-0112-9