A nanodevice with lifetime-improved singlet oxygen for enhanced photodynamic therapy

The short lifetime of singlet oxygen reduces its accumulation in the endoplasmic reticulum, which limits the output of photodynamic therapy. A nanodevice with functions of singlet oxygen production, storage and release can improve the lifetime of singlet oxygen for enhancing phototherapeutic efficac...

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 58; no. 42; pp. 6227 - 623
Main Authors Cao, A-Min, Liu, Wen-Long, Zou, Mei-Zhen, Qin, Si-Yong, Cheng, Yin-Jia, Zhang, Ai-Qing
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 24.05.2022
Subjects
Endoplasmic reticulum
Nanotechnology devices
Oxygen production
photochemotherapy
Photodynamic therapy
Singlet oxygen
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Summary:The short lifetime of singlet oxygen reduces its accumulation in the endoplasmic reticulum, which limits the output of photodynamic therapy. A nanodevice with functions of singlet oxygen production, storage and release can improve the lifetime of singlet oxygen for enhancing phototherapeutic efficacy. A nanodevice was designed with functions of singlet oxygen production, storage and release to improve the lifetime of singlet oxygen for enhancing photodynamic therapy.
Bibliography:https://doi.org/10.1039/d2cc01487d
Electronic supplementary information (ESI) available. See DOI
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ISSN:1359-7345
1364-548X
1364-548X
DOI:10.1039/d2cc01487d