Current concepts and challenges in managing ankle fractures in the presence of diabetes: A systematic review of the literature

• Published in: Journal of clinical orthopaedics and trauma Vol. 17; pp. 44 - 53
• Main Authors: Nash, William J., Hester, Thomas, Ha, Joon
• Format: Journal Article
• Language: English
• Published: India Elsevier B.V 01.06.2021; Elsevier
• Subjects: Amputation; Ankle Fractures; Charcot; Complication; Diabetes; Systematic review; Complication; Systematic review; Ankle Fractures; Diabetes; Charcot; Amputation
• ISSN: 0976-5662; 2213-3445
• DOI: 10.1016/j.jcot.2021.01.016

Ankle fractures in diabetic patients are known to have an increased morbidity. This systematic review aims to evaluate the current evidence in terms of risk profile and inform treatment options. Following the methodology of the Cochrane collaboration, an extensive literature search was conducted. Outcomes included, complications, operative and non-operative management and early weight-bearing. A total of 40 studies were included. Complication rates were higher in diabetic patients and more so in poorly controlled diabetes, IDDM, or “complicated” diabetes. Supplementary fixation was associated with lower complication rates. Regarding early weight-bearing, similar results to non-diabetics in the stable fracture pattern were found providing there was no evidence of neuropathy. Diabetes, especially complicated diabetes, presents an increased risk of complications. However non operative management of diabetic ankle fractures do poorly, and with the use of ‘ORIF plus’ techniques there is no increase in complications from early fixation. The use of external fixation for definitive fixation should be minimised as it is associated with high complication rates. •Diabetic patients with ankle fractures are at an increased risk of complications.•Diabetic patients with unstable ankle fractures have greater risks of complications when managed non-operatively.•Supplementary fixation in diabetic ankle fractures reduces the rate of complications.•Early weight-bearing in cast carries no additional risk in the absence of neuropathy.