Strategies to evaluate metabolic stress and catabolism by means of immunological variables

• Published in: Clinical Nutrition Vol. 19; no. 3; pp. 147 - 156
• Main Authors: Von Ruecker, A, Schmidt-Wolf, I.G.H
• Format: Book Review Conference Proceeding Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.06.2000; Elsevier
• Subjects: Apoptosis; Biological and medical sciences; Biomarkers; Cell Adhesion Molecules; Chemokines; Cytokines; Energy Metabolism - immunology; Evaluation Studies as Topic; Humans; Immunologic Tests; Immunological methods for diagnosis and exploration; Immunopathology; Medical sciences; Neurosecretory Systems - immunology; Neurosecretory Systems - metabolism; Other methods; Stress, Physiological - immunology; Stress, Physiological - metabolism; T-Lymphocytes, Helper-Inducer - immunology; T-Lymphocytes, Helper-Inducer - metabolism; Human; Immune response; Immunological investigation; T-Lymphocyte; Biological marker; Neuroendocrine regulation; Helper cell; Catabolism; Stress
• ISSN: 0261-5614; 1532-1983
• DOI: 10.1054/clnu.1999.0084

In this article, we outline how metabolic stress and catabolism are set off and influenced by the neuroendocrine network that interacts intensely with the immune system. When evaluating metabolic stress in individuals, the vast ocean of mediators, cell-surface markers and intracellular components that participate in metabolism and catabolic or anabolic changes make it necessary to focus on specific entities that may best mirror all these events. T cell responsiveness and factors that orchestrate the T helper type 1 and type 2 balance form an immunological mirror that can competently reflect catabolism and metabolic stress.