AIDS-related lymphoma
The incidence of intermediate and high grade B-cell non-Hodgkin’s lymphomas in HIV-infected individuals is approximately 60 times greater than in the general population. These AIDS-related lymphomas (AIDS-NHL) are a late manifestation of HIV infection and may increase in frequency as patients live l...
Saved in:
Published in | Blood reviews Vol. 13; no. 3; pp. 147 - 150 |
---|---|
Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Kent
Elsevier Ltd
01.09.1999
Elsevier |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The incidence of intermediate and high grade B-cell non-Hodgkin’s lymphomas in HIV-infected individuals is approximately 60 times greater than in the general population. These AIDS-related lymphomas (AIDS-NHL) are a late manifestation of HIV infection and may increase in frequency as patients live longer with highly active antiretroviral therapy and effective prophylaxis of opportunistic infections. AIDS-NHL have unique clinical and pathological features that are different from non-Hodgkin’s lymphomas in the general population. Histologically AIDS-NHL are either high (2/3) or intermediate (1/3) grade lymphomas. Clinically AIDS-NHL have a preponderance for extranodal involvement with central nervous system being the most common site for this. In addition to the clinical and pathological features of AIDS-NHL, a current knowledge of their pathogenesis and treatment options are presented in this review. |
---|---|
Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
ISSN: | 0268-960X 1532-1681 |
DOI: | 10.1054/blre.1999.0112 |