Multimodality Appearances of Marginal Zone Lymphoma Masquerading as Cryptogenic Organizing Pneumonia-serial Chest Radiograph and High-resolution Computed Tomography Appearances: ( 18 F) Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Staging Utility

Marginal zone lymphoma (MZL) is a group of low-grade, indolent, non-Hodgkin lymphomas rarely manifesting in the lungs. A 46-year-old man presenting with shortness of breath and cough was investigated and treated over 10 months for an atypical pattern of lung disease in keeping with cryptogenic organ...

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Bibliographic Details
Published inIndian journal of nuclear medicine Vol. 38; no. 4; pp. 400 - 401
Main Authors Robinson, Elizabeth, Nawwar, Ayah, Searle, Julie, Lyburn, Iain
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.10.2023
Medknow Publications & Media Pvt. Ltd
Wolters Kluwer - Medknow
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Summary:Marginal zone lymphoma (MZL) is a group of low-grade, indolent, non-Hodgkin lymphomas rarely manifesting in the lungs. A 46-year-old man presenting with shortness of breath and cough was investigated and treated over 10 months for an atypical pattern of lung disease in keeping with cryptogenic organizing pneumonia (COP). Initial lung biopsies were nondiagnostic - repeat sampling eventually showed MZL. Staging whole-body ( F) fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) demonstrated multisystem stage IV disease with intensely avid widespread pulmonary changes resembling COP. The case elegantly illustrates that pulmonary MZL can present insidiously masquerading as COP and shows the value of ( F) FDG PET/CT to stage extranodal MZL.
ISSN:0972-3919
0974-0244
DOI:10.4103/ijnm.ijnm_83_23