Brevundimonas spp. infection in immunocompromised children: Two case reports

Introduction Brevundimonas spp. are rare and opportunistic pathogens which may cause infections in patients who are immunocompromised or have underlying disease. Case report Two cases with a microbiological diagnosis of Brevundimonas aurantiaca and Brevundimonas spp. are presented. Both occurred in...

Full description

Saved in:
Bibliographic Details
Published inGerms (Bucureşti) Vol. 13; no. 1; pp. 72 - 79
Main Authors Altamirano-Beltran, Andree, Chiara-Chilet, Christian, Lopez, Jose W, Pons, Maria J, Maquera-Afaray, Julio
Format Journal Article
LanguageEnglish
Published Bucharest Asociatia pentru Cresterea Vizibilitatii Cercetarii Stiintifice (ACVCS) 01.03.2023
European HIV/AIDS and Infectious Diseases Academy
Subjects
Aminoglycosides
Antibacterial agents
Antimicrobial agents
Cancer
Cancer in children
Cardiovascular disease
Case reports
Catheters
Chemotherapy
Complications and side effects
Congenital diseases
Diagnosis
Disease susceptibility
Drug therapy
Gram-negative bacterial infections
Health aspects
Immunocompromised host
Infection
Infections
Infectious diseases
Leukemia
Liver cancer
Methods
Neutropenia
Pathogens
Patients
Pediatric research
Pediatrics
Risk factors
Peru
Online AccessGet full text

Cover

More Information
Summary:Introduction Brevundimonas spp. are rare and opportunistic pathogens which may cause infections in patients who are immunocompromised or have underlying disease. Case report Two cases with a microbiological diagnosis of Brevundimonas aurantiaca and Brevundimonas spp. are presented. Both occurred in immunocompromised patients with post-chemotherapy febrile neutropenia for B-type acute lymphoblastic leukemia and hepatoblastoma. Antibiogram findings showed resistance to quinolones, ceftazidime, and intermediate resistance to cefepime, being susceptible to carbapenems and aminoglycosides. The cases responded favorably to the administration of carbapenem. Conclusions The identification of the species and antimicrobial susceptibility profile favor response to infection, denoting the importance of species identification and the performance of an antibiogram to determine the different susceptibility profiles described in the literature on this emerging pathogen. Keywords Gram-negative aerobic bacteria, immunocompromised host, child.
ISSN:2248-2997
2248-2997
DOI:10.18683/germs.2023.1369