Bipolar Disorder Through Pregnancy and Postpartum

Lithium While lithium passes through breast milk and is measurable at approximately one quarter of the concentration of that in the mother in breast-feeding newborns, a recent study showed no serious adverse events were observed and elevations of thyroid-stimulating hormone, blood urea nitrogen, and...

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Bibliographic Details
Published inPsychiatric annals Vol. 42; no. 5; pp. 184 - 189
Main Authors Marsh, Wendy, Viguera, Adele
Format Journal Article
LanguageEnglish
Published Thorofare SLACK INCORPORATED 01.05.2012
Subjects
Bipolar disorder
Postpartum period
Psychotropic drugs
Womens health
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Summary:Lithium While lithium passes through breast milk and is measurable at approximately one quarter of the concentration of that in the mother in breast-feeding newborns, a recent study showed no serious adverse events were observed and elevations of thyroid-stimulating hormone, blood urea nitrogen, and creatinine were few, minor, and transient.40 Nonetheless, following maternal and infant lithium levels, infant BUN/Cr and TSH at 6 weeks may be advised, particularly if the infant shows symptoms of lithium exposure. Risk for morbidity associated with discontinuation of ongoing maintenance mood stabilizer treatment, particularly abruptly, are likely to be high for both the mother and her baby. [...]maintenance pharmacotherapy, in addition to appropriate psychosocial interventions, is recommended.
ISSN:0048-5713
1938-2456
DOI:10.3928/00485713-20120507-06