Transient-mode photothermal optical coherence tomography
Photothermal optical coherence tomography (PT-OCT) is an emerging extension of OCT, which forms images based on both scattering and absorption of light. The speed of PT-OCT, however, has been limited by the necessity for lock-in detection with extensive temporal sampling of the sample's PT resp...
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| Published in | Optics letters Vol. 46; no. 22; p. 5703 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
15.11.2021
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| Online Access | Get more information |
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| Summary: | Photothermal optical coherence tomography (PT-OCT) is an emerging extension of OCT, which forms images based on both scattering and absorption of light. The speed of PT-OCT, however, has been limited by the necessity for lock-in detection with extensive temporal sampling of the sample's PT response. Here, we demonstrate transient-mode PT-OCT (TM-PT-OCT), which increases the effective A-line rate by orders of magnitude from 10-100 Hz to 1.5-7.5 kHz, by interrogating the sample's transient thermal response to a single diode laser pulse. Functional imaging of moving samples with TM-PT-OCT at video rate is also presented. This significant improvement in imaging speed is expected to open the door for downstream integration of PT-OCT in clinical systems for in vivo imaging. |
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| ISSN: | 1539-4794 |
| DOI: | 10.1364/OL.443987 |