In vitro biocompatibility of equal channel angular processed (ECAP) titanium
This work attempts to understand the in vitro biocompatibility of ultrafine grained titanium prepared by the ECAP route. The results obtained from the mouse fibroblast cell line 3T3 showed a better cell adherence and cell proliferation on ECAP titanium specimen compared to the coarse grain Grade-2 T...
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Published in | Biomedical materials (Bristol) Vol. 2; no. 3; pp. S117 - S120 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
IOP Publishing
01.09.2007
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Abstract | This work attempts to understand the in vitro biocompatibility of ultrafine grained titanium prepared by the ECAP route. The results obtained from the mouse fibroblast cell line 3T3 showed a better cell adherence and cell proliferation on ECAP titanium specimen compared to the coarse grain Grade-2 Ti and Ti6Al4V alloy. This could be attributed to the increased surface energy and grain boundary energy and possibly the presence of a large number of nano-size conical groove-like structures (at triple point junctions of grain boundaries on the surface) in the ECAP Ti specimen compared to the coarse grain Grade-2 Ti and Ti6Al4V alloy. |
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AbstractList | This work attempts to understand the in vitro biocompatibility of ultrafine grained titanium prepared by the ECAP route. The results obtained from the mouse fibroblast cell line 3T3 showed a better cell adherence and cell proliferation on ECAP titanium specimen compared to the coarse grain Grade-2 Ti and Ti6Al4V alloy. This could be attributed to the increased surface energy and grain boundary energy and possibly the presence of a large number of nano-size conical groove-like structures (at triple point junctions of grain boundaries on the surface) in the ECAP Ti specimen compared to the coarse grain Grade-2 Ti and Ti6Al4V alloy. |
Author | Kim, Taik Nam Smetana, K Kim, W S Lee, B C Park, J K Panigrahi, B B Balakrishnan, A |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/18458454$$D View this record in MEDLINE/PubMed |
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SubjectTerms | 3T3 Cells Animals Biocompatible Materials - administration & dosage Biocompatible Materials - chemistry Cell Survival - drug effects Materials Testing Mice Surface Properties Titanium - administration & dosage Titanium - chemistry |
Title | In vitro biocompatibility of equal channel angular processed (ECAP) titanium |
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