In vitro biocompatibility of equal channel angular processed (ECAP) titanium

This work attempts to understand the in vitro biocompatibility of ultrafine grained titanium prepared by the ECAP route. The results obtained from the mouse fibroblast cell line 3T3 showed a better cell adherence and cell proliferation on ECAP titanium specimen compared to the coarse grain Grade-2 T...

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Bibliographic Details
Published inBiomedical materials (Bristol) Vol. 2; no. 3; pp. S117 - S120
Main Authors Kim, Taik Nam, Balakrishnan, A, Lee, B C, Kim, W S, Smetana, K, Park, J K, Panigrahi, B B
Format Journal Article
LanguageEnglish
Published England IOP Publishing 01.09.2007
Subjects
3T3 Cells
Animals
Biocompatible Materials - administration & dosage
Biocompatible Materials - chemistry
Cell Survival - drug effects
Materials Testing
Mice
Surface Properties
Titanium - administration & dosage
Titanium - chemistry
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Summary:This work attempts to understand the in vitro biocompatibility of ultrafine grained titanium prepared by the ECAP route. The results obtained from the mouse fibroblast cell line 3T3 showed a better cell adherence and cell proliferation on ECAP titanium specimen compared to the coarse grain Grade-2 Ti and Ti6Al4V alloy. This could be attributed to the increased surface energy and grain boundary energy and possibly the presence of a large number of nano-size conical groove-like structures (at triple point junctions of grain boundaries on the surface) in the ECAP Ti specimen compared to the coarse grain Grade-2 Ti and Ti6Al4V alloy.
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ISSN:1748-605X
1748-6041
1748-605X
DOI:10.1088/1748-6041/2/3/S06