Serum HSV-1 and 2 IgM in patients of sexually transmitted diseases

• Published in: Annals of tropical medicine and public health Vol. 5; no. 5; p. 479
• Main Authors: Tada, Dharmishtha, Khandelwal, Neeta
• Format: Journal Article
• Language: English
• Published: Accra Medknow Publications and Media Pvt. Ltd 01.09.2012; Medknow Publications & Media Pvt. Ltd
• Subjects: Care and treatment; Diagnosis; Health aspects; Herpes simplex virus; Herpes viruses; Immunoglobulin M; Sexually transmitted diseases; STD; India
• ISSN: 1755-6783; 0974-6005
• DOI: 10.4103/1755-6783.105138

Background: Herpes simplex virus type1 & 2 (HSV 1 & 2) are the causative agent for genital herpes. Aim: To examine Serum HSV-1 and 2 IgM in all type of STD (sexually transmitted disease) patients including Human immunodeficiency virus (HIV) infection and also to evaluate correlation of Serum HSV-1 and 2 IgM in these patients. Materials and Methods: 150 patients attending the STD clinic attached to a tertiary care hospital of Ahmedabad were included in the study. These all patients were screened for HIV-1 and 2 antibodies. Serum HSV-1 and 2 IgM correlations with HIV infection and clinical manifestations of genital herpes patients and other non herpetic STD patients were studied. Results: The overall Serum HSV-1 and 2 IgM in STD seroprevalence was 15.66%. Female have significant higher prevalence (p [less than] 0.05). STD cases and HSV seroprevalence were specially concentrated in persons aged 21 to 30 years. Among those positive with HSV, the distribution of STD are wide spread and found in non herpetic group at high frequency. Out of total 23 Serum HSV-1 and 2 IgM positive, 5 (21.73%) were HIV reactive. Discussion and Conclusion: Though Serum HSV-1 and 2 IgM in sexually transmitted diseases is less diagnostic, it helps to see the iceberg part of the infection among the population concerned recently. Putting STD surveillance systems in place specially in areas with high prevalence of HIV will be crucial in monitoring changes so that appropriate adjustments can be made to treatment schedules to make them more cost effective.