Plasma-membrane-associated immunoglobulins and other polypeptides of pig mesenteric node lymphocytes

Plasma membranes from pig mesenteric lymph-node lymphocytes contain a large number of polypeptide chains ranging in molecular weight from 20,000 to greater than 470,000, with a major component of 46,000. There are approx. 12-15 glycoproteins. The membranes contain immunoglobulin G, which comprises 0...

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Bibliographic Details
Published inBiochemical journal Vol. 148; no. 3; pp. 417 - 423
Main Authors Chavin, S I, Johnson, S M, Holliman, A
Format Journal Article
LanguageEnglish
Published England 01.06.1975
Subjects
Animals
Cell Membrane - immunology
Electrophoresis, Polyacrylamide Gel
Glycoproteins - analysis
Immune Sera
Immunodiffusion
Immunoglobulin G - analysis
Immunoglobulin M - analysis
Lymph Nodes - immunology
Lymphocytes - immunology
Microscopy, Electron
Molecular Weight
Peptides - analysis
Receptors, Antigen, B-Cell - analysis
Sheep - immunology
Swine
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Summary:Plasma membranes from pig mesenteric lymph-node lymphocytes contain a large number of polypeptide chains ranging in molecular weight from 20,000 to greater than 470,000, with a major component of 46,000. There are approx. 12-15 glycoproteins. The membranes contain immunoglobulin G, which comprises 0.6% of the total protein. Immunoglobulin M is also detected, but has not been accurately quantified for technical reasons. Possible origins of the membrane-associated immunoglobulin are briefly discussed. It is concluded that the immunoglobulin is probably associated with the plasma membrane in the intact cell.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0264-6021
1470-8728
DOI:10.1042/bj1480417