Paroxysmal kinesigenic dystonia after methylphenidate administration

We report a patient who developed paroxysmal kinesigenic dystonia shortly after initiation of therapy with methylphenidate for presumed attention deficit-hyperactivity disorder. Attacks persisted long after methylphenidate was discontinued and responded completely to treatment with carbamazepine. Th...

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Bibliographic Details
Published inJournal of child neurology Vol. 9; no. 1; p. 45
Main Authors Gay, C T, Ryan, S G
Format Journal Article
LanguageEnglish
Published United States 01.01.1994
Subjects
Adolescent
Attention Deficit Disorder with Hyperactivity - drug therapy
Carbamazepine - administration & dosage
Carbamazepine - therapeutic use
Dystonia - chemically induced
Dystonia - drug therapy
Humans
Male
Methylphenidate - adverse effects
Methylphenidate - therapeutic use
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Summary:We report a patient who developed paroxysmal kinesigenic dystonia shortly after initiation of therapy with methylphenidate for presumed attention deficit-hyperactivity disorder. Attacks persisted long after methylphenidate was discontinued and responded completely to treatment with carbamazepine. Though it is possible that methylphenidate caused this syndrome in our patient, it is more likely that the stimulant triggered the onset of a genetically determined disorder.
ISSN:0883-0738
DOI:10.1177/088307389400900110