Reactivity of some monoclonal antibodies specific for human lymphocytes with vervet monkey peripheral blood mononuclear cells

Reactivities of some monoclonal antibodies to human lymphocyte surface antigens were tested on vervet monkey peripheral blood mononuclear cells (PBMC), using flow cytometry and immunoperoxidase techniques. A number of antibodies were identified which reacted with similar populations of lymphocytes f...

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Bibliographic Details
Published inScandinavian journal of immunology. Supplement Vol. 11; p. 199
Main Author Olobo, J O
Format Journal Article
LanguageEnglish
Published England 01.01.1992
Subjects
Animals
Antibodies, Monoclonal - immunology
Cercopithecus aethiops
Humans
Leukocytes, Mononuclear - immunology
Lymphocytes - immunology
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Summary:Reactivities of some monoclonal antibodies to human lymphocyte surface antigens were tested on vervet monkey peripheral blood mononuclear cells (PBMC), using flow cytometry and immunoperoxidase techniques. A number of antibodies were identified which reacted with similar populations of lymphocytes from vervet monkeys. These included antibodies that define T cells, suppressor/cytotoxic cell subset, pan B cells, monocytes and MHC class I and II. A number of anti-CD4 markers examined were unsuitable for use in the vervet system.
ISSN:0301-6323
DOI:10.1111/j.1365-3083.1992.tb01652.x