Electrochemical behaviour of piperine. Comparison with control antioxidants

• Published in: Food chemistry Vol. 339; p. 128110
• Main Authors: Carp, Oana Elena, Moraru, Aurelian, Pinteala, Mariana, Arvinte, Adina
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.03.2021
• Subjects: Alkaloids - chemistry; Antioxidants - chemistry; Ascorbic Acid - chemistry; Benzodioxoles - chemistry; Biphenyl Compounds - chemistry; Cyclic N-Oxides - chemistry; Electrochemical Techniques; Electrooxidation; Free Radical Scavengers - chemistry; Free Radicals - metabolism; Hydrogen Peroxide - chemistry; Iron - chemistry; Oxidation-Reduction; Picrates - chemistry; Piperidines - chemistry; Piperine; Polyunsaturated Alkamides - chemistry; Potential antioxidant properties; Radical scavenging; Electrooxidation; Potential antioxidant properties; Piperine; Radical scavenging
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2020.128110

•Electrochemical methods applied for qualitative evaluation of antioxidant properties.•Piperine readily reacts with highly oxidizing radicals and bind redox-active metal ions.•Piperine, having no –OH group, acts in a similar manner as control phenolic antioxidants.•Piperine might possess antioxidant properties similar to control studied antioxidants.•Phenolic –OH group is not the only factor determining the antioxidant activity. Piperine, as the most abundant alkaloid in pepper, gained a lot of attention for possible antioxidant and therapeutic properties. Electrochemical techniques were applied to widely evaluate the redox behavior of piperine by comparison to that of well-known antioxidants: ascorbic acid, protocatechuic acid, syringic acid, tyrosine and capsaicin used as controls. Also, electrochemistry was involved in an innovative way to investigate the potential antioxidant properties of piperine combined with different in vitro peroxidation and reducing assays: (i) 1,1-diphenyl-2-picryl-hydrazyl free radical (DPPH) scavenging; (ii) 2,2,6,6-tetramethylpiperidinyl-1-oxy (TEMPO) scavenging; (iii) ferric ions (Fe3+) reducing power; (iv) hydrogen peroxide (H2O2) scavenging. Results show that piperine readily reacts with highly oxidizing radicals and bind redox-active metal ions in a similar manner as antioxidants used as model.