Vitamin B6 Neonatal Toxicity

Vitamin B6 is a micronutrient required by the body. It acts as a coenzyme in biochemical reactions. Vitamin B6 toxicity is not caused by the intake of food-based sources. The few reported cases of vitamin B6 toxicity are always caused by overdosing of nutritional supplements. Chronic toxicity typica...

Full description

Saved in:
Bibliographic Details
Published inCase reports in pediatrics Vol. 2022; pp. 3171351 - 4
Main Authors Guala, Andrea, Folgori, Giulia, Silvestri, Micaela, Barbaglia, Michelangelo, Danesino, Cesare
Format Journal Article
LanguageEnglish
Published United States Hindawi 06.12.2022
Hindawi Limited
Wiley
Subjects
Breastfeeding & lactation
Case Report
Case reports
Dietary supplements
Drug dosages
Electrocardiography
Fetuses
Gene expression
Glucose
Iatrogenesis
Kinases
Metabolism
Newborn babies
Nutrition
Patients
Pediatrics
Pregnancy
Self-medication
Toxicity
Online AccessGet full text

Cover

More Information
Summary:Vitamin B6 is a micronutrient required by the body. It acts as a coenzyme in biochemical reactions. Vitamin B6 toxicity is not caused by the intake of food-based sources. The few reported cases of vitamin B6 toxicity are always caused by overdosing of nutritional supplements. Chronic toxicity typically occurs with peripheral neuropathy such as paraesthesia, ataxia, and imbalance, paradoxically mimicking vitamin B6 deficiency. However, the prognosis is favorable, and symptoms usually show improvement once excessive vitamin B6 levels return to the physiological range. We report a newborn presenting with diffuse tremor at birth, interpreted as secondary to the mother's intake of high doses of a supplement containing vitamin B6 during pregnancy and breastfeeding. As expected, the newborn’s serum levels of vitamin B6 were high. The tremors disappeared when the maternal supplement was stopped.
Bibliography:Academic Editor: Junji Takaya
ISSN:2090-6803
2090-6811
DOI:10.1155/2022/3171351