Is buspirone effective for panic disorder?

• Published in: Journal of clinical psychopharmacology Vol. 10; no. 1; p. 3
• Main Authors: Sheehan, D V, Raj, A B, Sheehan, K H, Soto, S
• Format: Journal Article
• Language: English
• Published: United States 01.02.1990
• Subjects: Adult; Agoraphobia - drug therapy; Anxiety Disorders - drug therapy; Anxiety Disorders - psychology; Arousal - drug effects; Buspirone - therapeutic use; Double-Blind Method; Fear - drug effects; Female; Follow-Up Studies; Humans; Imipramine - therapeutic use; Male; Panic - drug effects; Phobic Disorders - drug therapy; Phobic Disorders - psychology; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Single-Blind Method

Buspirone was compared with imipramine and placebo in the treatment of panic disorder in an 8-week, double-blind controlled study of 52 randomly assigned patients. The side effect profile of buspirone was less disruptive than that of imipramine. Buspirone was not significantly superior to placebo in...