Is buspirone effective for panic disorder?

Buspirone was compared with imipramine and placebo in the treatment of panic disorder in an 8-week, double-blind controlled study of 52 randomly assigned patients. The side effect profile of buspirone was less disruptive than that of imipramine. Buspirone was not significantly superior to placebo in...

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Bibliographic Details
Published inJournal of clinical psychopharmacology Vol. 10; no. 1; p. 3
Main Authors Sheehan, D V, Raj, A B, Sheehan, K H, Soto, S
Format Journal Article
LanguageEnglish
Published United States 01.02.1990
Subjects
Adult
Agoraphobia - drug therapy
Anxiety Disorders - drug therapy
Anxiety Disorders - psychology
Arousal - drug effects
Buspirone - therapeutic use
Double-Blind Method
Fear - drug effects
Female
Follow-Up Studies
Humans
Imipramine - therapeutic use
Male
Panic - drug effects
Phobic Disorders - drug therapy
Phobic Disorders - psychology
Psychiatric Status Rating Scales
Randomized Controlled Trials as Topic
Single-Blind Method
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Summary:Buspirone was compared with imipramine and placebo in the treatment of panic disorder in an 8-week, double-blind controlled study of 52 randomly assigned patients. The side effect profile of buspirone was less disruptive than that of imipramine. Buspirone was not significantly superior to placebo in its antipanic or anxiolytic effects in panic disorder patients.
ISSN:0271-0749
DOI:10.1097/00004714-199002000-00002